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Calreticulin Antibodies
AND CALR ELISA kits, Calreticulin Proteins
Many biological assays use antibodies to detect Calreticulin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Calreticulin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Calreticulin antibodies...
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CALR Infographic by Boster Bio
All CALR Products
Product
Figures
Specificity
Applications
Price
Anti-CALR/Calreticulin Antibody
1 Citations 16 Q&As
Human, Mouse, Rat
IF, IHC, WB
$360
Cat # A00894
100 µl
Cat # A00894
100 µl
Anti-Calreticulin Rabbit Monoclonal Antibody
1 Citations 15 Q&As
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00894
100 μl
Cat # M00894
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1701
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1701
1 kit, containing one 96-well plate and all necessary reagents
Anti-Calreticulin/CALR Antibody Picoband®
1 Citations 7 Q&As
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00894-1
100 μg/vial
Cat # A00894-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00894-2
100 µg/vial
Cat # A00894-2
100 µg/vial
CALR Overview
Facts about Calreticulin.
Calreticulin (CALR)
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all the monoglucosylated glycoproteins that are synthesized in the ER.
Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation.
Gene Information
| Human | |
|---|---|
| Gene Name: | CALR |
| Uniprot: | P27797 |
| Entrez: | 811 |
Family
| Belongs to: |
|---|
| calreticulin family |
Alternative Names
Autoantigen Ro; CALR; Calregulin; Calreticulin; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; ERp60; FLJ26680; grp60; RO; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA; SSAHACBP; Vasostatin
Molecular Weight
Mass (kDA):
48.142 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.13 |
| Sequence: | 19; NC_000019.10 (12938609..12944489) |
Subcellular Localizations
Endoplasmic reticulum lumen. Cytoplasm, cytosol. Secreted, extracellular space, extracellular matrix. Cell surface. Sarcoplasmic reticulum lumen. Also found in cell surface (T cells), cytosol and extracellular matrix (PubMed:10358038). Associated with the lytic granules in the cytolytic T-lymphocytes.
Diseases
- Neoplasms
- Malignant Neoplasms
- Endoplasmic Reticulum Stress
- Physiological Stress
- Schizophrenia
- Psychotic Disorders
- Nervousness
- Adenocarcinoma
- Liver Carcinoma
- Adenocarcinoma Of Lung (disorder)
- Leukemia, Myelocytic, Acute
- Obesity
Interacting Proteins
- APP
- GABARAP
- HSPB1
- MTNR1A
- SMARCB1
- TAP1
Pathways
- Cell Proliferation
- Translation
- Pathogenesis
- Innervation
- Enucleation
- Response To Stress
- Glycosylation
- Tube Formation
- Immune Response
- Virulence
- Sporulation
- Localization
- Inflammatory Response
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Autophagy
- Cancer
- Cellular Markers
- ER Markers
- Membrane Trafficking and Chaperones
- Neuroscience
- Neurotransmission
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CALR
bosterbio.com/bosterbio-gene-info-cards/CALR
References
PMID: 2332496 by McCauliffe D.P., et al. Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen.
PMID: 1919005 by Rokeach L.A., et al. Characterization of the autoantigen calreticulin.
2 Publications of Boster Calreticulin Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.ijcard.2013.01.239, Calreticulin overexpression correlates with integrin-α5 and transforming growth...
- PubMed ID: 25695617, Wu C, Dong S, Li Y. Int J Mol Med. 2015 Apr;35(4):893-900. Doi: 10.3892/Ijmm.201...
*More publications can be found for each product on its corresponding product page