Calmodulin-2 Antibodies

AND CALM2 ELISA kits, Calmodulin-2 Proteins

Many biological assays use antibodies to detect Calmodulin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Calmodulin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Calmodulin-2 antibodies...

We validate the specificity of these antibodies to Calmodulin-2 by testing them on tissues known to express CALM2 positively and negatively. Browse below to find the CALM2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CALM2 Infographic by Boster Bio

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Calmodulin (CALM2) (NM_001743) Human Over-expression Lysate

Human

$628
Cat # LS000805
100 µg

CALM2 Overview

Facts about Calmodulin-2.

Calmodulin-2 (CALM2)

Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases.

Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (PubMed:16760425). Mediates calcium-dependent inactivation of CACNA1C (PubMed:26969752).

Gene Information

Human
Gene Name:	CALM2
Uniprot:	P0DP24
Entrez:	805

Family

Belongs to:

calmodulin family

Alternative Names

CALM; CALM1; CALM3; CALML2; calmodulin 2 (phosphorylase kinase, delta); calmodulin; CAM; CAM1; CAM2; CAM3; CAMB; CAMC; CAMII; CAMIII; FLJ99410; LP7057 protein; PHKD; PHKD2; phosphorylase kinase delta

Molecular Weight

Mass (kDA):
16.838 kDA

Genomic Context


Human

Location:	2p21
Sequence:	2; NC_000002.12 (47160082..47176936, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.

Diseases

Malignant Neoplasms
Neoplasms
Glaucoma
Blind Vision
Obstruction Of Trachea
Primary Congenital Glaucoma
Malignant Neoplasm Of Breast
Glaucoma, Open-angle
Dysplasia
Tumor Angiogenesis
Glycogen Storage Disease
Pain

Lymphoma
Mammary Neoplasms
Osteoporosis
Osteoarthritis Of Hip
Abnormal Degeneration
Adenocarcinoma

Pathways

Pathogenesis
Localization
Cell Adhesion
Cell Proliferation
Membrane Organization
Cellular Process
Metaphase
Lung Growth
Regeneration
Dna Amplification
Reverse Transcription
Translation

Cell Death
Cell Communication
Angiogenesis
Oncogenesis
Mitochondrial Membrane Organization
Cell-cell Adhesion

PTMs

Phosphorylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CALM2

References

PMID: 2445749 by Sengupta B., et al. Molecular analysis of human and rat calmodulin complementary DNA clones. Evidence for additional active genes in these species.

PMID: 9681195 by Toutenhoofd S.L., et al. Characterization of the human CALM2 calmodulin gene and comparison of the transcriptional activity of CALM1, CALM2 and CALM3.