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- Table of Contents
1 Citations 4 Q&As
Facts about CAD protein.
Human | |
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Gene Name: | CAD |
Uniprot: | P27708 |
Entrez: | 790 |
Belongs to: |
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No superfamily |
CAD protein; CAD trifunctional protein; carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, anddihydroorotase; EC 2.1.3.2; EC 3.5.2.3; EC 6.3.5; EC 6.3.5.5; multifunctional protein CAD
Mass (kDA):
242.984 kDA
Human | |
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Location: | 2p23.3 |
Sequence: | 2; NC_000002.12 (27217369..27243943) |
Cytoplasm. Nucleus. Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth.
PMID: 8619816 by Iwahana H., et al. Molecular cloning of a human cDNA encoding a trifunctional enzyme of carbamoyl-phosphate synthetase-aspartate transcarbamoylase- dihydroorotase in de Novo pyrimidine synthesis.
PMID: 1979741 by Davidson J.N., et al. Organization and nucleotide sequence of the 3' end of the human CAD gene.
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