Bloc1s5 Antibodies

AND Bloc1s5 ELISA kits, Bloc1s5 Proteins

Many biological assays use antibodies to detect Bloc1s5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bloc1s5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bloc1s5 antibodies...

We validate the specificity of these antibodies to Bloc1s5 by testing them on tissues known to express Bloc1s5 positively and negatively. Browse below to find the Bloc1s5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Bloc1s5 Infographic by Boster Bio

All Bloc1s5 Products

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Product

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Specificity

Applications

Price

Muted (BLOC1S5) (NM_201280) Human Recombinant Protein

$813
Cat # PROTQ8TDH9
20 µg

Muted (BLOC1S5) (NM_201280) Human Over-expression Lysate

Human

$628
Cat # LS063915
100 µg

Bloc1s5 Overview

Facts about Biogenesis of lysosome-related organelles complex 1 subunit 5.

Biogenesis of lysosome-related organelles complex 1 subunit 5 (Bloc1s5)

Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is needed to target membrane protein cargos into vesicles constructed at cell bodies for delivery into neurites and nerve terminals.

The BLOC-1 complex, in association with SNARE proteins, is also suggested to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.

Gene Information

Mouse
Gene Name:	Bloc1s5
Uniprot:	Q8R015
Entrez:	17828

Family

Belongs to:

BLOC1S5 family

Alternative Names

DKFZp686E2287; FLJ18427; MUdJ303A1.3; muted homolog (mouse); protein Muted homolog

Molecular Weight

Mass (kDA):
21.283 kDA

Genomic Context


Mouse

Location:	13 A3.3\|13 18.35 cM
Sequence:	13;

Tissue Specificity

Detected in heart, brain, spleen, lung, kidney and testis.

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Bloc1s5

References

PMID: 11912185 by Zhang Q., et al. The gene for the muted (mu) mouse, a model for Hermansky-Pudlak syndrome, defines a novel protein which regulates vesicle trafficking.

PMID: 12019270 by Falcon-Perez J.M., et al. BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules.