Bhlha15 Antibodies

AND Bhlha15 ELISA kits, Bhlha15 Proteins

Many biological assays use antibodies to detect Bhlha15, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bhlha15 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bhlha15 antibodies...

We validate the specificity of these antibodies to Bhlha15 by testing them on tissues known to express Bhlha15 positively and negatively. Browse below to find the Bhlha15 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Bhlha15 Infographic by Boster Bio

All Bhlha15 Products

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Product

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Specificity

Applications

Price

Anti-BHLHA15 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A10502
0.1 mg

BHLHA15 (NM_177455) Human Over-expression Lysate

Human

$628
Cat # LS168620
100 µg

Bhlha15 Overview

Facts about Class A basic helix-loop-helix protein 15.

Class A basic helix-loop-helix protein 15 (Bhlha15)

Plays a role in controlling the transcriptional activity of MyoD, making sure that enlarging myoblast populations remain undifferentiated (PubMed:17612490). Repression may happen through muscle-specific E-box occupancy by homodimers.

May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity.

Gene Information

Mouse
Gene Name:	Bhlha15
Uniprot:	Q9QYC3
Entrez:	17341

Family

Belongs to:

No superfamily

Alternative Names

basic helix-loop-helix domain containing, class B, 8; basic helix-loop-helix family, member a15; bHLHa15; BHLHB8; class A basic helix-loop-helix protein 15; Class B basic helix-loop-helix protein 8; class II bHLH protein MIST1; MIST1MIST-1; Muscle, intestine and stomach expression 1

Molecular Weight

Mass (kDA):
22.15 kDA

Genomic Context


Mouse

Location:	5\|5 G2
Sequence:	5;

Tissue Specificity

Expressed in pancreatic tissue only in acinar cells. There is a complete absence of expression in intra- or interlobular pancreatic ducts and in all islet cells.

Diseases

Acinar Cell Carcinoma
Pancreatitis
Adenocarcinoma
Pancreatitis, Chronic
Pancreatic Ductal Adenocarcinoma
Pancreatic Neoplasm
Anaplasia

Ductal Breast Carcinoma

Pathways

Cell Maturation
Cell Dedifferentiation
Dedifferentiation
Localization
Secretion

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Bhlha15

References

PMID: 10575209 by Pin C.L., et al. Cloning of the murine Mist1 gene and assignment to mouse chromosome band 5G2-5G3.

PMID: 9073453 by Lemercier C., et al. Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern.