BUB1 Antibodies

AND BUB1 ELISA kits, BUB1 Proteins

Many biological assays use antibodies to detect BUB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BUB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BUB1 antibodies...

We validate the specificity of these antibodies to BUB1 by testing them on tissues known to express BUB1 positively and negatively. Browse below to find the BUB1 antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BUB1 Infographic by Boster Bio

All BUB1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Bub1 Antibody Picoband®

5 Q&As

Human, Mouse, Rat

$370
Cat # PB9135
100 μg/vial

Anti-Bub1 Antibody

Human, Mouse

ELISA, IF, ICC, WB

$449
Cat # A00776
0.1 mg

Anti-BUB1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A00776-1
100ul

Anti-Bub1 Antibody Picoband®

Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A00776-2
100 μg/vial

BUB1 (NM_004336) Human Recombinant Protein

$813
Cat # PROTO43683
20 µg

Anti-Bub1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # M00776-1
100 μl/vial

Anti-BUB1 Antibody Picoband®

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A00776-3
100 μg/vial

BUB1 (NM_004336) Human Over-expression Lysate

Human

$628
Cat # LS000699
100 µg

BUB1 Overview

Facts about Mitotic checkpoint serine/threonine-protein kinase BUB1.

BUB1 3D structure. Source: alphafold

Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1)

Serine/threonine-protein kinase that performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Has a key role in the gathering of checkpoint proteins at the kinetochore, needing the subsequent localization of CENPF, BUB1B, CENPE and MAD2L1.

Required for the kinetochore localization of PLK1. Required for centromeric enrichment of AUKRB in prometaphase.

Gene Information

Human
Gene Name:	BUB1
Uniprot:	O43683
Entrez:	699

Family

Belongs to:

protein kinase superfamily

Alternative Names

BUB1 budding uninhibited by benzimidazoles 1 homolog; Bub1; BUB1Amitotic checkpoint serine/threonine-protein kinase BUB1; BUB1L; budding uninhibited by benzimidazoles 1 (yeast homolog); budding uninhibited by benzimidazoles 1 homolog (yeast); EC 2.7.11.1; hBUB1mitotic spindle checkpoint kinase; putative serine/threonine-protein kinase

Molecular Weight

Mass (kDA):
122.375 kDA

Genomic Context


Human

Location:	2q13
Sequence:	2; NC_000002.12 (110637528..110678107, complement)

Tissue Specificity

High expression in testis and thymus, less in colon, spleen, lung and small intestine. Expressed in fetal thymus, bone marrow, heart, liver, spleen and thymus. Expression is associated with cells/tissues with a high mitotic index.

Subcellular Localizations

Nucleus. Chromosome, centromere, kinetochore. Nuclear in interphase cells. Accumulates gradually during G1 and S phase of the cell cycle, peaks at G2/M, and drops dramatically after mitosis. Localizes to the outer kinetochore. Kinetochore localization is required for normal mitotic timing and checkpoint response to spindle damage and occurs very early in prophase. AURKB, KNL1 and INCENP are required for kinetochore localization (By similarity).