Protein BTG2 Antibodies

Protein BTG2 (BTG2)

Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent Method.

In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation.

Gene Information

Human
Gene Name:	BTG2
Uniprot:	P78543
Entrez:	7832

Family

Belongs to:
BTG family

Alternative Names

B-cell translocation gene 2; BTG family member 2; BTG family, member 2; MGC126063; MGC126064; NGF-inducible proliferative protein PC3; PC3nerve growth factor-inducible proliferative; pheochromacytoma cell-3; protein BTG2; TIS21

Molecular Weight

Mass (kDA):
17.416 kDA

Genomic Context

Human
Location:	1q32.1
Sequence:	1; NC_000001.11 (203305519..203309602)

Diseases

• Neoplasms
• Malignant Neoplasms
• Carcinoma
• Malignant Neoplasm Of Breast
• Mammary Neoplasms
• Cell Transformation, Neoplastic
• Carcinogenesis
• Nervousness
• Inflammation
• Malignant Paraganglionic Neoplasm
• Malignant Neoplasm Of Prostate
• Neoplasm Metastasis
• Prostatic Neoplasms

• Leukemia
• Cell Invasion
• Hyperplasia
• Growth Arrest
• Pheochromocytoma
• Liver Carcinoma
• Liver Neoplasms

Interacting Proteins

• AR
• CNOT7
• Cnot7
• CNOT8

Pathways

• Cell Cycle
• Cell Proliferation
• Neurogenesis
• Cell Growth
• Cell Differentiation
• Cell Cycle Arrest
• Cell Death
• Methylation
• Dna Repair
• G1 Phase
• Pathogenesis
• S Phase
• Localization

• Regeneration
• Cell Division
• Translation
• Cell Migration
• Regulation Of Gene Expression
• Mitosis
• Protein Methylation

PTMs

• Phosphorylation
• Methylation
• Acetylation
• Demethylation

• Reduction
• Cleavage
• Deacetylation
• Oxidation

• Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BTG2

Best Uses Of The BTG2 Marker

The BTG2 marker can be utilized to serve a variety of functions such as molecule Sieve Column analysis and SDS–PAGE. This is a fantastic choice for molecular weight markers on SDS-PAGE gels as well as molecular sieve columns for gel filtration. The process of making polypeptides is popular with the skilled biochemist. Most of the time, BTG-2 can be prepared in the laboratory.

Vari

The BTG2 marker is a genetic change in a gene known as BTG. The progression of PTDLBCL has been associated with the BTG2 gene. In a study on this disease in which the BTG2 mutation was a reliable predictor for poor prognosis. The study included patients suffering from DLBCL of all subtypes as well as different BTG2 mutation status. The study also showed that BTG2 mutations are associated with poor prognosis. The study also showed that mutations of BTG2 were independent factors linked to poor outcomes in PT-DLBCL patients.

In comparison to the BTG2 wild-type group, the one with the mutation showed no significant differences in overall survival (ODS). The group with the mutation had higher RR than the mutant group. BTG2 was not significantly different in the wt group as it was in the mutated. The BTG2 mutation group had a higher rate of patients dying from non-hemorrhagic cerephalopathy.

A molecule-based weight marker

A Boster Bio Molecular weight marker can be used for qualitative analysis of proteins in different samples. This marker is a combination of anticathepsin (CTSB) activity and an fluorescent dye. It can be used to detect tumors, and is particularly useful in clinical trials that require targeted chemotherapy or radiotherapy. The CTSB molecule is located in the tumor's margins and is an important regulator of the immune response. It also plays a key role in the process of tumor angiogenesis.

SDS-PAGE

The SDS-PAGE technique is a popular technique to analyze proteins. The amount of protein present in the sample will determine the degree of sensitivity of the technique. In addition to ensuring that the protein concentration is uniform it can also determine the identity and molecular mass of proteins. The SDS-PAGE method can be used for various applications for purification of proteins and molecular mass measurement and identification of proteins.

For SDS-PAGE, the solution contains a sample buffer and running buffer. The sample buffer has the 2% LDS detergent. The protein solution is added to the sample buffer and heated to 70deg C. The buffer is containing 0.1 percent SDS and EDTA to enhance the removal of metal ions. In addition, the run buffer is made up of 0.1% SDS and 1 millimeter EDTA.

Here are a few advantages of SDS-PAGE. BN-PAGE does not denaturate proteins, however it is a great choice for the separation of sensitive proteins. This type of gel allows the detection of significant enzyme activity without causing degradation of proteins. The BTG2 marker is a protein that moves in bands with different molecular weights.

The results can be used to create species, samples and applications. Scientists who use this marker may receive product credits. These guidelines apply to all scientists across the world. The BTG2 protein is an extensively used biological marker. These methods can also be used to confirmation of antibodies against BTG2 protein. But, it is important to remember that the results of your research must be presented to an established research institute.

Molecular sieve columns

Molecular sieves are commonly employed in desiccant processes. They remove oxygen from nitrogen and absorb moisture from liquids, oil and gas samples. These purification solutions are based on cutting-edge PSA technology and employ 13X molecular sieves in beads or pellets. Pure oxygen can be created which is the ideal product. The healthcare industry has numerous advantages from Molecular Sieve 13X.

The BTG-2 polypeptide is best utilized in molecular sieve gel filtration procedures. It can also be used in molecular sieve columns , and as a molecularweight marker on SDS/PAGE gels. Experts are well-versed in the method of preparation used for the polypeptide. Its properties make it ideal to be used for a variety of research purposes, and the BTG2 marker is utilized in a variety of applications.

In addition The BTG-2 marker is useful for analyzing genes. It can be used for determining the number of cells produced. By identifying the BTG-2 gene researchers can develop therapeutics that specifically target cells that are underproducing. The BTG-2 gene encodes the protein that is part of the BTG-1 family. It is present in human and murine tissues.

The BTG2 gene is described as a degenerate genetic cod. Anyone with normal skills will recognize that DNA that has been deposited contains numerous nucleic acids with the same sequence. A polypeptide with BTG-2 protein activity or BTG-3 will be identified. The BTG-2 gene has been used successfully for a long time to detect cancerous cells.