BMPR1B Antibodies

AND BMPR1B ELISA kits, BMPR1B Proteins

Many biological assays use antibodies to detect BMPR1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BMPR1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BMPR1B antibodies...

We validate the specificity of these antibodies to BMPR1B by testing them on tissues known to express BMPR1B positively and negatively. Browse below to find the BMPR1B antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BMPR1B Infographic by Boster Bio

All BMPR1B Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-BMPR1B Antibody Picoband®

1 Q&As

Human

IHC, WB

$370
Cat # PB9528
100 μg/vial

Anti-BMPR1B Antibody Picoband®

3 Q&As

Human, Mouse, Rat

$370
Cat # PA2017
100 μg/vial

Anti-BMPR1B Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A02722-1
100ul

Human BMPR-IB/ALK-6 Recombinant Protein

SDS-PAGE

$250
Cat # PROTO00238
Starting from 4ug

BMPR1B (NM_001203) Human Over-expression Lysate

Human

$628
Cat # LS000658
100 µg

BMPR1B Overview

Facts about Bone morphogenetic protein receptor type-1B.

BMPR1B 3D structure. Source: alphafold

Bone morphogenetic protein receptor type-1B (BMPR1B)

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.

Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.

Gene Information

Human
Gene Name:	BMPR1B
Uniprot:	O00238
Entrez:	658

Family

Belongs to:

protein kinase superfamily

Alternative Names

activin receptor-like kinase 6; ALK-6; ALK6CDw293; BMP type-1B receptor; BMPR1B; BMPR-1B; BMPRIB; BMPR-IB; bone morphogenetic protein receptor type-1B; bone morphogenetic protein receptor, type IB; CDw293 antigen; CDw293; EC 2.7.11; EC 2.7.11.30; serine/threonine receptor kinase

Molecular Weight

Mass (kDA):
56.93 kDA

Genomic Context


Human

Location:	4q22.3
Sequence:	4; NC_000004.12 (94757955..95158453)

Subcellular Localizations

Cell membrane. Membrane; Single-pass type I membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Brachydactyly
Mammary Neoplasms
Nervousness
Tumor Angiogenesis
Brachydactyly, Type A2
Carcinoma
Malignant Neoplasm Of Prostate
Limb Deformities, Congenital
Neoplasm Metastasis

Colonic Neoplasms
Cell Transformation, Neoplastic
Congenital Abnormality
Prostatic Neoplasms
Fracture
Ovarian Neoplasm
Dysequilibrium Syndrome

Interacting Proteins

BMP2
GDF5

Pathways

Ovulation
Cell Proliferation
Osteoblast Differentiation
Localization
Cell Differentiation
Pathogenesis
Angiogenesis
Regeneration
Cell Growth
Neurogenesis
Cell Cycle
Lung Development
Ossification

Limb Development
Chondrocyte Proliferation
Axon Guidance
Eye Development
Ameloblast Differentiation
Dedifferentiation
Gene Silencing

PTMs

Phosphorylation
Cleavage

Demethylation
Sumoylation

Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BMPR1B

References

PMID: 9178898 by Ide H., et al. Cloning of human bone morphogenetic protein type IB receptor (BMPR- IB) and its expression in prostate cancer in comparison with other BMPRs.

PMID: 10051328 by Astroem A.-K., et al. Chromosomal localization of three human genes encoding bone morphogenetic protein receptors.