Bcl11a Antibodies

AND Bcl11a ELISA kits, Bcl11a Proteins

Many biological assays use antibodies to detect Bcl11a, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bcl11a in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bcl11a antibodies...

We validate the specificity of these antibodies to Bcl11a by testing them on tissues known to express Bcl11a positively and negatively. Browse below to find the Bcl11a antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Bcl11a Infographic by Boster Bio

All Bcl11a Products

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Product

Figures

Specificity

Applications

Price

Anti-Ctip1 Monoclonal Antibody

7 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M00741
100 μl

Anti-Ctip1 BCL11A Antibody

Human

Flow Cytometry, IHC, WB

$405
Cat # A00741
100ul

CTIP1 (BCL11A) (NM_022893) Human Over-expression Lysate

Human

$960
Cat # LS053335
100 µg

Bcl11a Overview

Facts about B-cell lymphoma/leukemia 11A.

B-cell lymphoma/leukemia 11A (Bcl11a)

Functions as a myeloid and B-cell proto-oncogene.
May play important roles in leukemogenesis and hematopoiesis.

A vital element in lymphopoiesis, is needed for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1.

Gene Information

Mouse
Gene Name:	Bcl11a
Uniprot:	Q9QYE3
Entrez:	14025

Family

Belongs to:

No superfamily

Alternative Names

B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2; B-cell CLL/lymphoma 11A (zinc finger protein); B-cell CLL/lymphoma 11A; B-cell lymphoma/leukemia 11A; BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1; BCL-11A; BCL11A-S; BCL11A-XL; C2H2-type zinc finger protein; COUP-TF-interacting protein 1; CTIP1ecotropic viral integration site 9; ecotropic viral integration site 9 homolog; Ecotropic viral integration site 9 protein homolog; EVI-9; EVI9FLJ34997; HBFQTL5; KIAA1809BCL11A-L; Zinc finger protein 856; ZNF856FLJ10173

Molecular Weight

Mass (kDA):
83.855 kDA

Genomic Context


Mouse

Location:	11\|11 A3.2
Sequence:	11;

Tissue Specificity

Isoforms are expressed in a tissue-specific fashion. Isoforms 1, isoform 2, and isoform 3 are expressed at similar levels in testis, kidney and spleen. Isoform 1 is expressed in the stomach, and isoform 2 is expressed exclusively in the lung. Overexpression following proviral integration in hematopoietic cells results in the generation of myeloid leukemia.

Diseases

Anemia, Sickle Cell
Leukemia
Beta Thalassemia
Lymphoma
Malignant Neoplasms
Neoplasms
Anemia
B-cell Lymphomas
Lymphoid Leukemia
Chronic Lymphocytic Leukemia
Thalassemia
Chromosomal Translocation
Diabetes Mellitus

Diabetes Mellitus, Non-insulin-dependent
Hemoglobinopathies
Hemoglobin F Disease
Hodgkin Disease
Myeloid Leukemia
Cell Transformation, Neoplastic
Diffuse Large B-cell Lymphoma

Pathways

Pathogenesis
Cell Development
Gene Silencing
Interphase
Cell Proliferation
Secretion
Cell Fate Specification
Translation
Insulin Secretion
Localization
Methylation
Innervation
Cell Activation

Developmental Process
Dna Hypomethylation
Brain Development
Aging
Neurogenesis
B Cell Activation
Ribosome Assembly

PTMs

Deacetylation
Phosphorylation

Acetylation
Methylation

Sumoylation

Research Areas

Apoptosis
Cancer
Inhibitors, Activators and Regulators
Transcription Factors and Regulators
Tumor Suppressors

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Bcl11a

References

PMID: 10757802 by Nakamura T., et al. Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell proto-oncogene product.

PMID: 10744719 by Avram D., et al. Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors.