BAI1-associated protein 3 Antibodies

AND BAIAP3 ELISA kits, BAI1-associated protein 3 Proteins

Many biological assays use antibodies to detect BAI1-associated protein 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BAI1-associated protein 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BAI1-associated protein 3 antibodies...

We validate the specificity of these antibodies to BAI1-associated protein 3 by testing them on tissues known to express BAIAP3 positively and negatively. Browse below to find the BAIAP3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BAIAP3 Infographic by Boster Bio

All BAIAP3 Products

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Price

Anti-BAP3 BAIAP3 Antibody

Human

ELISA, IF, IHC-P, WB

$449
Cat # A12383
0.1 mg

BAIAP3 (NM_003933) Human Recombinant Protein

$1062
Cat # PROTO94812
20 µg

BAIAP3 (NM_003933) Human Over-expression Lysate

Human

$960
Cat # LS008938
100 µg

BAIAP3 Overview

Facts about BAI1-associated protein 3.

BAIAP3 3D structure. Source: alphafold

BAI1-associated protein 3 (BAIAP3)

Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network.

By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones. May regulate behavior and food consumption by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin (PubMed:28626000).

Gene Information

Human
Gene Name:	BAIAP3
Uniprot:	O94812
Entrez:	8938

Family

Belongs to:

unc-13 family

Alternative Names

BAI1-associated protein 3; BAI-associated protein 3; BAP3KIAA0734MGC138334

Molecular Weight

Mass (kDA):
131.901 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (1333645..1349441)

Tissue Specificity

Predominantly expressed in brain (PubMed:9790924). Also expressed in nonneural tissues such as breast and testes epithelium (PubMed:12498718).

Subcellular Localizations

Cytoplasm, cytosol. Recycling endosome membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Rapidly recruited to the plasma membrane and to Golgi structures in response to increased intracellular calcium concentration.

Diseases

Desmoplastic
Desmoplastic Small Round Cell Tumor
Malignant Neoplasms
Neoplasms
Sarcoma
Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)
Chimera Disorder
Small Cell Carcinoma Of Lung
Sclerosis
Monosomy
Mood Disorders
Malignant Neoplasm Of Breast

Alpha-thalassemia
Carcinoma
Parkinson Disease
Osteosarcoma
Tumor Angiogenesis
Asthma
Secondary Parkinson Disease

Pathways

Exocytosis
Cell Proliferation
Translation
Dna Recombination
Metaphase
Angiogenesis

Rna Processing

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BAIAP3

References

PMID: 9790924 by Shiratsuchi T., et al. Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1.

PMID: 12498718 by Palmer R.E., et al. Induction of BAIAP3 by the EWS-WT1 chimeric fusion implicates regulated exocytosis in tumorigenesis.