Ataxin-10 Antibodies

AND ATXN10 ELISA kits, Ataxin-10 Proteins

Many biological assays use antibodies to detect Ataxin-10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ataxin-10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ataxin-10 antibodies...

We validate the specificity of these antibodies to Ataxin-10 by testing them on tissues known to express ATXN10 positively and negatively. Browse below to find the ATXN10 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATXN10 Infographic by Boster Bio

All ATXN10 Products

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Product

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Specificity

Applications

Price

Anti-Ataxin-10 ATXN10 Antibody

Human, Mouse, Rat

$405
Cat # A04898
100ul

ATXN10 (NM_001167621) Human Recombinant Protein

$813
Cat # PROTQ9UBB4
20 µg

ATXN10 (NM_013236) Human Over-expression Lysate

Human

$628
Cat # LS025814
100 µg

ATXN10 Overview

Facts about Ataxin-10.

ATXN10 3D structure. Source: alphafold

Ataxin-10 (ATXN10)

Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway.

May play a role in the maintenance of a critical intracellular glycosylation degree and homeostasis. .

Gene Information

Human
Gene Name:	ATXN10
Uniprot:	Q9UBB4
Entrez:	25814

Family

Belongs to:

ataxin-10 family

Alternative Names

ataxin 10; ataxin-10; Brain protein E46 homolog; E46L; FLJ37990; HUMEEP; SCA10spinocerebellar ataxia 10; Spinocerebellar ataxia type 10 protein

Molecular Weight

Mass (kDA):
53.489 kDA

Genomic Context


Human

Location:	22q13.31
Sequence:	22; NC_000022.11 (45671798..45845307)

Tissue Specificity

Expressed in the central nervous system.

Subcellular Localizations

Cytoplasm, perinuclear region.

Diseases

Ataxia
Ataxia, Spinocerebellar
Cerebellar Ataxia
Neurodegenerative Disorders
Epilepsy
Polyneuropathy
Trinucleotide Repeat Expansion
Dysarthria
Myotonic Dystrophy
Nerve Degeneration
Nervous System Disorder
Friedreich Ataxia

Oncogene Activation Process
Pregnancy Complications
Retinal Degeneration
Insulinoma
Congenital Cerebral Hernia
Neoplasms

Pathways

Pathogenesis
Glycosylation
Dna Replication
Cell Death
Cellular Senescence
Hypersensitivity
Localization
Cell Cycle Arrest
Cytokinesis
Senescence
Gene Conversion

Nucleosome Assembly
Translation
Cell Cycle
Rna Processing
Rna Interference
Rna Polyadenylation

PTMs

Phosphorylation
Glycosylation

Acetylation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATXN10

References

PMID: 15201271 by Maerz P., et al. Ataxin-10, the spinocerebellar ataxia type 10 neurodegenerative disorder protein, is essential for survival of cerebellar neurons.

PMID: 16498633 by Waragai M., et al. Ataxin 10 induces neuritogenesis via interaction with G-protein beta2 subunit.