AGPAT1 Antibodies

AND AGPAT1 ELISA kits, AGPAT1 Proteins

Many biological assays use antibodies to detect AGPAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AGPAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AGPAT1 antibodies...

We validate the specificity of these antibodies to AGPAT1 by testing them on tissues known to express AGPAT1 positively and negatively. Browse below to find the AGPAT1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AGPAT1 Infographic by Boster Bio

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Anti-AGPAT1 Antibody

Human, Mouse, Rat

IP, WB

$405
Cat # A09272
100ul

AGPAT1 Overview

Facts about 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha.

AGPAT1 3D structure. Source: alphafold

1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (AGPAT1)

Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety in the sn-2 position of the glycerol backbone. .

Gene Information

Human
Gene Name:	AGPAT1
Uniprot:	Q99943
Entrez:	10554

Family

Belongs to:

1-acyl-sn-glycerol-3-phosphate acyltransferase family

Alternative Names

1-acylglycerol-3-phosphate O-acyltransferase 1 (acetoacetly Coenzyme Athiolase); 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acidacyltransferase, alpha); 1-acylglycerol-3-phosphate O-acyltransferase 1; 1-AGP acyltransferase 1; 1-AGPAT1; EC 2.3.1.51; G15; LPAATA; LPAAT-alpha1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; Lysophosphatidic acid acyltransferase alpha; lysophospholipid acyltransferase; MGC4007,1-AGPAT 1; MGC5423; Protein G15

Molecular Weight

Mass (kDA):
31.717 kDA

Genomic Context


Human

Location:	6p21.32
Sequence:	6; NC_000006.12 (32168212..32178108, complement)

Tissue Specificity

Widely expressed. Expressed in adipose tissue and at high levels in testis and pancreas. Expressed at lower levels in tissues such as heart, brain, placenta, kidney, lung, spleen, thymus, prostate, ovary, intestine, colon, leukocyte and liver.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Insulin Resistance
Malignant Neoplasms
Lipodystrophy
Diabetes Mellitus
Familial Generalized Lipodystrophy
Neurodegenerative Disorders
Coronary Artery Disease
Neoplasms
Papillary Adenocarcinoma
Malignant Neoplasm Of Ovary
Long Chain Acyl-coa Dehydrogenase Deficiency
Insulin Resistance - Type A
Hypothalamic Syndrome

Ovarian Neoplasm
Fatty Liver
Adenocarcinoma
Hereditary Diseases
Steatohepatitis
Steatosis
Hyperinsulinism

Interacting Proteins

MEOX2

Pathways

Transport
Fatty Acid Transport
Translation
Circadian Rhythm
Glycosylation
Fatty Acid Oxidation

Myoblast Differentiation

PTMs

Glycosylation

Oxidation

Acylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AGPAT1

References

PMID: 9212163 by West J., et al. Cloning and expression of two human lysophosphatidic acid acyltransferase cDNAs that enhance cytokine-induced signaling responses in cells.

PMID: 9291118 by Stamps A.C., et al. A human cDNA sequence with homology to non-mammalian lysophosphatidic acid acyltransferases.