ANKRD11 Antibodies

AND ANKRD11 ELISA kits, ANKRD11 Proteins

Many biological assays use antibodies to detect ANKRD11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ANKRD11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ANKRD11 antibodies...

We validate the specificity of these antibodies to ANKRD11 by testing them on tissues known to express ANKRD11 positively and negatively. Browse below to find the ANKRD11 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ANKRD11 Infographic by Boster Bio

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ANKRD11 Overview

Facts about Ankyrin repeat domain-containing protein 11.

ANKRD11 3D structure. Source: alphafold

Ankyrin repeat domain-containing protein 11 (ANKRD11)

Chromatin regulator which modulates histone acetylation and gene expression in neural precursor cells (By similarity). May recruit histone deacetylases (HDACs) to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation (PubMed:15184363).

Has a role in proliferation and growth of cortical neural precursors (PubMed:25556659). May also regulate bone homeostasis (By similarity).

Gene Information

Human
Gene Name:	ANKRD11
Uniprot:	Q6UB99
Entrez:	29123

Family

Belongs to:

No superfamily

Alternative Names

ANCO-1; ANCO1ankyrin repeat domain-containing protein 11; ankyrin repeat domain 11; Ankyrin repeat-containing cofactor 1; ankyrin repeat-containing protein 11; LZ16; nasopharyngeal carcinoma susceptibility protein; T13

Molecular Weight

Mass (kDA):
297.913 kDA

Genomic Context


Human

Location:	16q24.3
Sequence:	16; NC_000016.10 (89267619..89490561, complement)

Subcellular Localizations

Nucleus. Localizes to chromatin during prometaphase.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Dwarfism
Haploinsufficiency
Short Stature, Characteristic Facies, Macrodontia, Mental Retardation, And Skeletal Anomalies
Macrodontia
Autistic Disorder
Carcinoma
Mammary Neoplasms
Cancer Of Nasopharynx
Impaired Cognition

Tooth Abnormalities
Bone Diseases, Developmental
Developmental Delay (disorder)
Cognition Disorders
Autism Spectrum Disorders
Neoplasm Metastasis
Fused Incisors

Pathways

Methylation
System Development
Nervous System Development
Dna Methylation
Central Nervous System Development
Pathogenesis

PTMs

Demethylation

Acetylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANKRD11

References

PMID: 15184363 by Zhang A., et al. Identification of a novel family of ankyrin repeats-containing cofactors for p160 nuclear receptor coactivators.

PMID: 21782149 by Sirmaci A., et al. Mutations in ANKRD11 cause KBG syndrome, characterized by intellectual disability, skeletal malformations, and macrodontia.