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- Table of Contents
Facts about ATP-binding cassette sub-family B member 9.
Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine aren't favored. .
Human | |
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Gene Name: | ABCB9 |
Uniprot: | Q9NP78 |
Entrez: | 23457 |
Belongs to: |
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ABC transporter superfamily |
ABC transporter 9 protein; ATP-binding cassette sub-family B member 9; ATP-binding cassette transporter 9; ATP-binding cassette, sub-family B (MDR/TAP), member 9; EC 3.6.3; EC 3.6.3.44; EST122234; hABCB9; KIAA1520; TAPL; TAP-like protein
Mass (kDA):
84.475 kDA
Human | |
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Location: | 12q24.31 |
Sequence: | 12; NC_000012.12 (122917324..122975160, complement) |
Highly expressed in testis, and at moderate levels in brain, spinal cord, and thyroid. Not expressed in monocytes but strongly expressed during differentiation of monocytes to dendritic cells and macrophages.
Lysosome membrane; Multi-pass membrane protein. May be located in membrane rafts.
PMID: 11011155 by Kobayashi A., et al. A half-type ABC transporter TAPL is highly conserved between rodent and man, and the human gene is not responsive to interferon-gamma in contrast to TAP1 and TAP2.
PMID: 10748049 by Zhang F., et al. Characterization of ABCB9, an ATP binding cassette protein associated with lysosomes.