Product Info Summary
SKU: | A04215 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-TSPY1L Antibody
SKU/Catalog Number
A04215
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TSPY1L Antibody (Catalog # A04215). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
TSPY1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TSPY1L Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04215)
Host
Rabbit
Contents
TSPY1L Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal TSPY1L antibody was raised against a 20 amino acid peptide near the carboxy terminus of human TSPY1L. The immunogen is located within the last 50 amino acids of TSPY1L.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
TSPY1L antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist; this antibody will detect only TSPY1L.
Reactive Species
A04215 is reactive to TSPY1 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
35012 MW
Background of TSPY1
Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04215 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TSPY1L antibody can be used for detection of TSPY1L by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of TSPY1L in A20 cell lysate with TSPY1L antibody at (A) 0.5 and (B) 1 μg/mL
Protein Target Info & Infographic
Gene/Protein Information For TSPY1 (Source: Uniprot.org, NCBI)
Gene Name
TSPY1
Full Name
Testis-specific Y-encoded protein 1
Weight
35012 MW
Superfamily
nucleosome assembly protein (NAP) family
Alternative Names
CT78, TSPY, DYS14, pJA923, Testis-specific Y-encoded protein 1, CT78 TSPY1 CT78, DYS14, TSPY, pJA923 testis specific protein Y-linked 1 testis-specific Y-encoded protein 1|cancer/testis 78|testis specific protein, Y-linked
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TSPY1, check out the TSPY1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TSPY1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TSPY1L Antibody (A04215)
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