Anti-SR-4 HTR4 Antibody

Product Name

Anti-SR-4 HTR4 Antibody

View all 5-HT4 Antibodies

SKU/Catalog Number

A03681-1

Size

100μl

Form

Liquid

Description

Boster Bio Anti-SR-4 HTR4 Antibody catalog # A03681-1. Tested in WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SR-4 HTR4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03681-1)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the N-terminal region of human SR-4. at AA rangle: 40-120

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A03681-1 is reactive to HTR4 in Mouse, Rat

Applications

A03681-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

43761 MW

Background of 5-HT4

CAND1 is also known as TIP120A, and TATA-binding protein-interacting protein 120A. The SCF complex consists of the invariable components Skp1, Cul1, and Rbx1 as well as a variable F-box protein, and functions as an E3 ubiquitin ligase. E3 ubiquitin ligases regulate various physiological processes. CAND1 binds to Cul1 and potentially regulates the SCF complex. CAND1 physically associates with Cul1 in the nucleus and this interaction is mediated by a central region of Cul1 distinct from its binding sites for Skp1 and Rbx1. CAND1 selectively binds to unneddylated CUL1 and is dissociated by CUL1 neddylation. CAND1 forms a ternary complex with CUL1 and ROC1.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of specific cells using SR-4 Polyclonal antibody.

Gene/Protein Information For HTR4 (Source: Uniprot.org, NCBI)

Alternative Names

5HT4; 5-HT4; 5-HT-4; 5-HT4R; 5-hydroxytryptamine (serotonin) receptor 4,5-hydroxytryptamine receptor 4,5-HT45-hydroxytryptamine4 receptor; cardiac 5-HT4 receptor; HTR4; Serotonin receptor 4 HTR4 5-HT4, 5-HT4R 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 4|5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled|5-hydroxytryptamine receptor 4 transcript variant b2|5-hydroxytryptamine receptor 4 transcript variant b3|cardiac 5-HT4 receptor

For more info on HTR4, check out the HTR4 Infographic

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In this infographic, you will see the following information for HTR4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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