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Product Info Summary
| SKU: | MA1090 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | WB |
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Product info
Product Name
Anti-Spectrin(Alpha And Beta) SPTB Antibody (Monoclonal, SB-SP1)
View all Spectrin beta 1 Antibodies
SKU/Catalog Number
MA1090
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Spectrin (Alpha And Beta) SPTB Antibody (Monoclonal, SB-SP1) catalog # MA1090. Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Spectrin(Alpha And Beta) SPTB Antibody (Monoclonal, SB-SP1) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1090)
Host
Mouse
Contents
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Clonality
Monoclonal
Clone Number
SB-SP1
Isotype
Mouse IgG1
Immunogen
Human erythrocyte spectrin.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
MA1090 is reactive to SPTB in Human
Reconstitution
Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Observed Molecular Weight
60 kDa
Calculated molecular weight
246329 MW
Background of Spectrin beta 1
Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2. Spectrin mutations cause spinocerebellar ataxia type 5.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
MA1090 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 2-4μg/ml, Human
Validation Images & Assay Conditions
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Boster Kit Box
Protein Target Info & Infographic
Gene/Protein Information For SPTB (Source: Uniprot.org, NCBI)
Gene Name
SPTB
Full Name
Spectrin beta chain, erythrocytic
Weight
246329 MW
Superfamily
spectrin family
Alternative Names
Erythroid spectrin beta ;Sptb ;LOC314251 ; SPTB EL3, HS2, HSPTB1, SPH2 spectrin beta, erythrocytic spectrin beta chain, erythrocytic|Sp beta|beta-I spectrin|membrane cytoskeletal protein|spectrin beta Tandil|spectrin beta chain, erythrocyte
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SPTB, check out the SPTB Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SPTB: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Spectrin(Alpha And Beta) SPTB Antibody (Monoclonal, SB-SP1) (MA1090)
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