Anti-RNF130 Antibody

Product Name

Anti-RNF130 Antibody

View all RNF130 Antibodies

SKU/Catalog Number

A12501

Size

100μl

Form

Liquid

Description

Boster Bio Anti-RNF130 Antibody catalog # A12501. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-RNF130 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12501)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Monoclonal

Clone Number

7B1

Isotype

IgG

Immunogen

Synthesized peptide derived from the C-terminal region of human RNF130. at AA rangle: 200-280

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A12501 is reactive to RNF130 in Human, Mouse, Rat

Applications

A12501 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

46405 MW

Background of RNF130

COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of specific cells using RNF130 Polyclonal antibody.

Gene/Protein Information For RNF130 (Source: Uniprot.org, NCBI)

Alternative Names

E3 ubiquitin-protein ligase RNF130; EC 2.1.1; EC 6.3.2; EC 6.3.2.-; g1-related zinc finger protein; G1RZFP; Goliath homolog; GOLIATH; GP; H-Goliath; MGC117241; MGC99542; ring finger protein 130MGC138647 RNF130 G1RP, G1RZFP, GOLIATH, GP ring finger protein 130 E3 ubiquitin-protein ligase RNF130|RING-type E3 ubiquitin transferase RNF130|g1-related zinc finger protein|goliath homolog

For more info on RNF130, check out the RNF130 Infographic

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In this infographic, you will see the following information for RNF130: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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