Click image to see more details
Product Info Summary
| SKU: | PA1859 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-PTCH2 Antibody Picoband®
View all Patched 2/PTCH2 Antibodies
SKU/Catalog Number
PA1859
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-PTCH2 Antibody catalog # PA1859. Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PTCH2 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1859)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human PTCH2, different from the related mouse sequence by one amino acid.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA1859 is reactive to PTCH2 in Human, Mouse
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
50 kDa
Calculated molecular weight
130544 MW
Background of Patched 2/PTCH2
PTCH2 (patched 2), also known as PTC2, encodes a 1.203-amino acid putative transmembrane protein that is highly homologous to the PTCH product. The Patched-hedgehog signaling pathway is involved in establishing segment polarity and the anterior-posterior orientation of a number of developing appendages. The pathway is conserved from fly to vertebrates and has been implicated in a number of human neoplasms and developmental syndromes. Mutations in the human Patched gene are the basis of the nevoid basal cell carcinoma syndrome. With age, homozygous mutant male mice developed skin lesions consisting of alopecia and epidermal hyperplasia, suggesting a role for Ptch2 in adult epidermal homeostasis via Shh signaling.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PA1859 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Human, Mouse
Positive Control
WB: HELA Cell
Validation Images & Assay Conditions
Click image to see more details
Anti-PTCH2 antibody, PA1859, Western blotting
WB: HELA Cell Lysate
Protein Target Info & Infographic
Gene/Protein Information For PTCH2 (Source: Uniprot.org, NCBI)
Gene Name
PTCH2
Full Name
Protein patched homolog 2
Weight
130544 MW
Superfamily
patched family
Alternative Names
Protein patched homolog 2;PTC2;PTCH2;UNQ560/PRO1121/PRO57079; PTCH2 PTC2 patched 2 protein patched homolog 2|patched homolog 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PTCH2, check out the PTCH2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PTCH2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PTCH2 Antibody Picoband® (PA1859)
Hello CJ!
No publications found for PA1859
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-PTCH2 Antibody Picoband®?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
0 Reviews For Anti-PTCH2 Antibody Picoband®
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
2 Customer Q&As for Anti-PTCH2 Antibody Picoband®
Question
We are currently using anti-PTCH2 antibody PA1859 for mouse tissue, and we are well pleased with the WB results. The species of reactivity given in the datasheet says human, mouse. Is it possible that the antibody can work on pig tissues as well?
Verified Customer
Verified customer
Asked: 2020-04-09
Answer
The anti-PTCH2 antibody (PA1859) has not been tested for cross reactivity specifically with pig tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in pig you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2020-04-09
Question
Is PA1859 suitable for staining cells and/or tissue sections?
Verified customer
Asked: 2019-05-07
Answer
Our lab technicians have tested the Anti-PTCH2 Antibody (PA1859) for staining cells and/or tissue sections and it did not test well for these applications. So, we only recommend using this antibody for Western Blot application.
Boster Scientific Support
Answered: 2019-05-07
