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Product Info Summary
| SKU: | A04774 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-PRRX1 Antibody
SKU/Catalog Number
A04774
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-PRRX1 Antibody (Catalog # A04774). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
PRRX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-PRRX1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04774)
Host
Rabbit
Contents
PRRX1 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
PRRX1 antibody was raised against a 19 amino acid peptide near the center of human PRRX1. The immunogen is located within amino acids 70 - 120 of PRRX1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
PRRX1 antibody is human, mouse and rat reactive. At least two isoforms of PRRX1 are known to exist; this antibody will detect both isoforms.
Reactive Species
A04774 is reactive to PRRX1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
27296 MW
Background of PRRX1
The paired related homeobox protein 1 (PRRX1) is a paired-type DNA-binding homeodomain that plays an important role as a key switch for neural cell lineage determination and is essential for development (1,2). PRRX1 is expressed in a number of undifferentiated mesenchymal cells in mouse embryos and adults (3). Mice with a disrupted PRRX1 gene show perinatal death with craniofacial and limb malformations (4). Low PRRX1 expression levels were significantly associated with metastasis and poor prognosis of breast and colorectal cancer (5).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04774 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PRRX1 antibody can be used for detection of PRRX1 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PRRX1 in HeLa cell lysate with PRRX1 antibody at 1 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For PRRX1 (Source: Uniprot.org, NCBI)
Gene Name
PRRX1
Full Name
Paired mesoderm homeobox protein 1
Weight
27296 MW
Superfamily
paired homeobox family
Alternative Names
Paired related homeobox 1, homeobox protein PHOX1, Paired mesoderm homeobox protein 1, PHOX1, PMX1, PRX1, PRX-1 PRRX1 AGOTC, PHOX1, PMX1, PRX-1, PRX1 paired related homeobox 1 paired mesoderm homeobox protein 1|homeobox protein PHOX1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PRRX1, check out the PRRX1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PRRX1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PRRX1 Antibody (A04774)
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No publications found for A04774
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