Anti-Protein SOGA1 SOGA1 Antibody

Product Name

Anti-Protein SOGA1 SOGA1 Antibody

View all SPACA9 Antibodies

SKU/Catalog Number

A13046

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Protein SOGA1 SOGA1 Antibody (Catalog # A13046). Tested in ELISA, WB, IF applications. This antibody reacts with Human.

Storage & Handling

SOGA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-Protein SOGA1 SOGA1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13046)

Host

Rabbit

Contents

SOGA1 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

SOGA1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SOGA. The immunogen is located within the last 50 amino acids of SOGA1 .

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

SOGA1 antibody is human specific. At least four isoforms of SOGA1 are known to exist.

Reactive Species

A13046 is reactive to SOGA1 in Human

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

159760 MW

Background of SPACA9

The recently identified protein suppressor of glucose by autophagy protein 1 (SOGA1) has been found to be involved in the regulation of autophagy (1). SOGA1 is thought to contribute to adiponectin-mediated insulin-dependent inhibition of autophagy during the activation of adenosine monophosphate kinase (AMPK) (1,2). SOGA1 contains an internal signal peptide that enables the secretion of a circulating fragment of SOGA1, providing a surrogate marker for intracellular SOGA1 levels (2). Knockdown of SOGA1 elevated glucose production in primary hepatocytes indicates that SOGA1 is an inhibitor of glucose production. It thus might be useful as a novel therapeutic target for diabetes (3).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A13046 is guaranteed for ELISA, IF, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

SOGA1 antibody can be used for detection of SOGA1 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For SOGA1 (Source: Uniprot.org, NCBI)

Alternative Names

SOGA, KIAA0889, C20orf117, SOGA, Protein SOGA1, SOGA family member 1, 80-kDa SOGA fragment SOGA1 C20orf117, KIAA0889, SOGA suppressor of glucose, autophagy associated 1 protein SOGA1|SOGA family member 1|suppressor of glucose by autophagy|suppressor of glucose from autophagy|suppressor of glucose, autophagy-associated protein 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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