Product Info Summary
SKU: | A11283 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-Protein lifeguard 1 GRINA Antibody
SKU/Catalog Number
A11283
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Protein lifeguard 1 GRINA Antibody (Catalog # A11283). Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
GRINA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Protein lifeguard 1 GRINA Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11283)
Host
Rabbit
Contents
GRINA Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal GRINA antibody was raised against an 18 amino acid peptide near the center of human GRINA. The immunogen is located within amino acids 110 - 160 of GRINA.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
GRINA antibody is predicted to not cross-react with other members of the TMBIM family.
Reactive Species
A11283 is reactive to GRINA in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
41203 MW
Background of NMDARA1
The transmembrane BAX inhibitor motif (TMBIM) family of proteins includes the founder member TMBIM6/BI-1, TMBIM1/RECS1 (responsive to centrifugal force and shear stress gene 1 protein), TMBIM2/LFG (life guard), TMBIM3/GRINA (glutamate receptor ionotropic NMDA protein 1), TMBIM4/GAAP (Golgi anti-apoptotic-associated protein), and TMBIM5/GHTIM (growth hormone-inducible transmembrane protein). They are highly conserved in mammals and zebrafish and contain a conserved BAX inhibitor-1 motif. GRINA is expressed in the brain and is a potential apoptotic regulator.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11283 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
GRINA antibody can be used for detection of GRINA by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of GRINA in human testis tissue lysate with GRINA antibody at (A) 1 and (B) 2 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For GRINA (Source: Uniprot.org, NCBI)
Gene Name
GRINA
Full Name
Protein lifeguard 1
Weight
41203 MW
Superfamily
BI1 family
Alternative Names
LFG1, HNRGW, TMBIM3, NMDARA1, LFG1, Protein lifeguard 1, NMDA receptor glutamate-binding subunit GRINA HNRGW, LFG1, NMDARA1, TMBIM3 glutamate ionotropic receptor NMDA type subunit associated protein 1 protein lifeguard 1|NMDA receptor glutamate-binding subunit|glutamate [NMDA] receptor-associated protein 1|glutamate receptor, NMDA subtype, glutamate-binding subunit|glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)|lifeguard 1|putative MAPK-activating protein PM02|transmembrane BAX inhibitor motif containing 3|transmembrane BAX inhibitor motif-containing protein 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GRINA, check out the GRINA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GRINA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Protein lifeguard 1 GRINA Antibody (A11283)
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