Product Info Summary
SKU: | P03512-1 |
---|---|
Size: | 100μl |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-Phospho-Glycogen Synthase 1 (S645) Antibody
View all Glycogen Synthase Antibodies
SKU/Catalog Number
P03512-1
Size
100μl
Form
Liquid
Description
Boster Bio Anti-Phospho-Glycogen Synthase 1 (S645) Antibody catalog # P03512-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-Glycogen Synthase 1 (S645) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # P03512-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Glycogen Synthase 1 around the phosphorylation site of S645.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
P03512-1 is reactive to GYS1 in Human, Mouse, Rat
Applications
P03512-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
52 kDa
Calculated molecular weight
83786 MW
Background of Glycogen Synthase
DARPP-32 is a dopamine (DA) and cAMP-regulated ~32k phosphoprotein that is associated with dopaminoceptive neurons (Fienberg et al., 1998). The protein inhibits protein phosphatase I when it is phosphorylated on Thr-34. In contrast, when DARPP-32 is phosphorylated on Thr-75 the protein acts as an inhibitor of PKA (Bibb et al., 1999). Phosphorylation of DARPP-32 is thought to play a critical role in the regulation of dopaminergic neurotransmission. In addition, the activity of DARPP-32 is also thought to play important roles in the actions of alcohol, caffeine and Prozac® (Maldve et al., 2002; Lindskog et al., 2002; Svenningsson et al., 2002).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB, 1:500-1:2000
Validation Images & Assay Conditions
![p03512 1 western blotting analysis 1 p03512 1 western blotting analysis 1](https://www.bosterbio.com/media/catalog/product/p/0/p03512-1-western-blotting-analysis-1.jpg)
Click image to see more details
Western Blot (WB) analysis of 293 cells using Phospho-Glycogen Synthase 1 (S645) Polyclonal antibody.
Protein Target Info & Infographic
Gene/Protein Information For GYS1 (Source: Uniprot.org, NCBI)
Gene Name
GYS1
Full Name
Glycogen [starch] synthase, muscle
Weight
83786 MW
Superfamily
glycosyltransferase 3 family
Alternative Names
EC 2.4.1.11; glycogen [starch] synthase, muscle; glycogen synthase 1 (muscle); GYSGSY GYS1 GSY, GYS glycogen synthase 1 glycogen [starch] synthase, muscle|glycogen synthase 1 (muscle)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GYS1, check out the GYS1 Infographic
![GYS1 infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GYS1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-Glycogen Synthase 1 (S645) Antibody (P03512-1)
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No publications found for P03512-1
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