This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
, No Gclids
PDGFRA Antibodies
AND PDGFRA ELISA kits, PDGFRA Proteins
Many biological assays use antibodies to detect PDGFRA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDGFRA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDGFRA antibodies...
Previous: CBLIF
Next: PDGFRL
PDGFRA Infographic by Boster Bio
All PDGFRA Products
Product
Figures
Specificity
Applications
Price
Anti-PDGF Receptor alpha/PDGFRA Antibody Picoband®
3 Citations 16 Q&As
Human, Mouse, Rat
IHC, WB
$370
Cat # PB9771
100 μg/vial
Cat # PB9771
100 μg/vial
Anti-PDGFR alpha Antibody
1 Citations 16 Q&As
Human, Mouse, Rat
ELISA, IF, IHC-P, ICC, WB
$335
Cat # A30446
100ul
Cat # A30446
100ul
Anti-PDGFR alpha Rabbit Monoclonal Antibody
2 Citations 4 Q&As
Human, Mouse, Rat
WB
$370
Cat # M00366
100 μl
Cat # M00366
100 μl
Human, Mouse
ELISA
$480
Cat # EKC1447
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1447
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2106
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2106
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2587
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2587
1 kit, containing two 96-well plates and all necessary reagents
Human
Flow Cytometry, ICC
$308
Cat # M00366-1
0.1 mg
Cat # M00366-1
0.1 mg
Human, Mouse, Rat
ELISA, IHC, WB
$380
Cat # A00366Y849-1
100ul
Cat # A00366Y849-1
100ul
Human, Mouse, Rat
ELISA, IHC, WB
$380
Cat # A00366Y754-1
100ul
Cat # A00366Y754-1
100ul
Human, Mouse, Rat
IHC, WB
$523
Cat # M00366-2
100 µl
Cat # M00366-2
100 µl
Human
$960
Cat # LS005156
100 µg
Cat # LS005156
100 µg
PDGFRA Overview
Facts about Platelet-derived growth factor receptor alpha.
Platelet-derived growth factor receptor alpha (PDGFRA)
Tyrosine-protein kinase that functions as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Based on the circumstance, promotes or inhibits cell proliferation and cell migration.
Plays an essential role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton growth and cephalic closure during embryonic development.
Gene Information
| Human | |
|---|---|
| Gene Name: | PDGFRA |
| Uniprot: | P16234 |
| Entrez: | 5156 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; CD140a; EC 2.7.10; EC 2.7.10.1; MGC74795; PDGF R alpha; PDGFR alpha; PDGFR2; PDGFRA; PDGFRA/BCR fusion; PDGF-R-alpha; platelet-derived growth factor receptor, alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein; RHEPDGFRA
Molecular Weight
Mass (kDA):
122.67 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q12 |
| Sequence: | 4; NC_000004.12 (54229127..54298247) |
Tissue Specificity
Detected in platelets (at protein level). Widely expressed. Detected in brain, fibroblasts, smooth muscle, heart, and embryo. Expressed in primary and metastatic colon tumors and in normal colon tissue.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Cell projection, cilium. Golgi apparatus.
Diseases
- Neoplasms
- Gastrointestinal Stromal Tumors
- Malignant Neoplasms
- Stromal Neoplasm
- Malignant Paraganglionic Neoplasm
- Neoplasm Metastasis
- Leukemia
- Eosinophilia
- Hypereosinophilic Syndrome
- Sarcoma
- Carcinoma
- Stomach Neoplasms
- Gastrointestinal Neoplasms
Interacting Proteins
- CCDC155
- CRK
- CRKL
- EGFR
- PDGFA
- PDGFB
- PDGFC
- PDGFRB
Pathways
- Pathogenesis
- Localization
- Cell Proliferation
- Cell Growth
- Drug Resistance
- Oncogenesis
- Cell Cycle
- Methylation
- Reverse Transcription
- Angiogenesis
- Transport
- Cell Differentiation
PTMs
- Phosphorylation
- Methylation
- Cleavage
- Dephosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDGFRA
bosterbio.com/bosterbio-gene-info-cards/PDGFRA
References
PMID: 2544881 by Claesson-Welsh L., et al. cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor.
PMID: 2536956 by Matsui T., et al. Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes.
4 Publications of Boster PDGFRA Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.celrep.2018.10.063, Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression
- PubMed ID: 10.1016/j.anireprosci.2019.05.006, Effect of maternal feed restriction in dairy goats at different stages of gestat...
- PubMed ID: 29140299, PDGFR%u03B1 regulated by miR-34a and FoxO1 promotes adipogenesis in porcine intr...
- PubMed ID: 27446356, Label-retaining assay enriches tumor-initiating cells in glioblastoma spheres cu...
*More publications can be found for each product on its corresponding product page