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Product Info Summary
| SKU: | A07034-1 |
|---|---|
| Size: | 80 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IF, WB |
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Product info
Product Name
Anti-PCGF6 Antibody (C-term)
SKU/Catalog Number
A07034-1
Size
80 µl
Description
Boster Bio Anti-PCGF6 Antibody (C-term) (Catalog # A07034-1). Tested in IF, WB application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-PCGF6 Antibody (C-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07034-1)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This PCGF6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 261-295 amino acids from the C-terminal region of human PCGF6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A07034-1 is reactive to PCGF6 in Human
Reconstitution
Calculated molecular weight
39047 Da
Background of Pcgf6
Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07034-1 is guaranteed for IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IF: 1:25
WB: 1:1000
Validation Images & Assay Conditions
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Fluorescent image of Hela cells stained with PCGF6 Antibody (C-term). A07034-1 was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).
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Western blot analysis of lysate from human kidney tissue, using PCGF6 Antibody (C-term). A07034-1 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
Protein Target Info & Infographic
Gene/Protein Information For PCGF6 (Source: Uniprot.org, NCBI)
Gene Name
PCGF6
Full Name
Polycomb group RING finger protein 6
Weight
39047 Da
Alternative Names
Polycomb group RING finger protein 6, Mel18 and Bmi1-like RING finger, RING finger protein 134, PCGF6, MBLR, RNF134 Pcgf6|4933407A11Rik, AI604840, MB, MBLR, Rnf1, Rnf134|polycomb group ring finger 6|polycomb group RING finger protein 6|Mel18- and Bmi1-like RING finger protein|ring finger protein 134
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PCGF6, check out the PCGF6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PCGF6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PCGF6 Antibody (C-term) (A07034-1)
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