Product Info Summary
SKU: | PA2128 |
---|---|
Size: | 100 μg/vial |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-P2X6/P2RX6 Antibody Picoband®
View all P2X6/P2RX6 Antibodies
SKU/Catalog Number
PA2128
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-P2X6/P2RX6 Antibody catalog # PA2128. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-P2X6/P2RX6 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2128)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human P2X6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA2128 is reactive to P2RX6 in Human
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
39 kDa
Calculated molecular weight
48829 MW
Background of P2X6/P2RX6
Purinergic receptor P2X-Like 1, also known as P2X6, is a protein that in humans is encoded by the P2RX6 gene. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. This gene belongs to the family of P2X receptors. P2RXL1 gene was mapped to chromosome 22q11 by fluorescence in situ hybridization. This gene is a receptor for ATP that acts as a ligand-gated ion channel. It can mediate rapid and selective permeability to cations.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PA2128 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Human
Positive Control
WB: U87 Cell, 22RV1 Cell, JURKAT Cell, HT1080 Cell,
Validation Images & Assay Conditions
Click image to see more details
Anti-P2X6 antibody, PA2128, Western blotting
Lane 1: U87 Cell Lysate
Lane 2: 22RV1 Cell Lysate
Lane 3: JURKAT Cell Lysate
Lane 4: HT1080 Cell Lysate
Protein Target Info & Infographic
Gene/Protein Information For P2RX6 (Source: Uniprot.org, NCBI)
Gene Name
P2RX6
Full Name
P2X purinoceptor 6
Weight
48829 MW
Superfamily
P2X receptor family
Alternative Names
P2X purinoceptor 6;P2X6;ATP receptor;P2XM;Purinergic receptor;Purinergic receptor P2X-like 1;P2RX6;P2RXL1, P2X6; P2RX6 P2RXL1, P2X6, P2XM purinergic receptor P2X 6 P2X purinoceptor 6|ATP receptor|purinergic receptor P2X, ligand gated ion channel, 6|purinergic receptor P2X-like 1, orphan receptor|purinoceptor P2X6|purinoreceptor P2X6|skeletal muscle-expressed P2X
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on P2RX6, check out the P2RX6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for P2RX6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-P2X6/P2RX6 Antibody Picoband® (PA2128)
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No publications found for PA2128
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Customer Q&As
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5 Customer Q&As for Anti-P2X6/P2RX6 Antibody Picoband®
Question
Is there a BSA free version of anti-P2X6/P2RX6 antibody PA2128 available?
Verified Customer
Verified customer
Asked: 2020-01-29
Answer
Thank you for your recent telephone inquiry. I can confirm that some lots of this anti-P2X6/P2RX6 antibody PA2128 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.
Boster Scientific Support
Answered: 2020-01-29
Question
Is this PA2128 anti-P2X6/P2RX6 antibody reactive to the isotypes of P2RX6?
Verified Customer
Verified customer
Asked: 2019-11-07
Answer
The immunogen of PA2128 anti-P2X6/P2RX6 antibody is A synthetic peptide corresponding to a sequence at the C-terminus of human P2X6(387-406aa VWRELALASQARLAECLRRS). Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?
Boster Scientific Support
Answered: 2019-11-07
Question
Does anti-P2X6/P2RX6 antibody PA2128 work on goat WB with brain?
Verified Customer
Verified customer
Asked: 2019-10-02
Answer
Our lab technicians have not validated anti-P2X6/P2RX6 antibody PA2128 on goat. You can run a BLAST between goat and the immunogen sequence of anti-P2X6/P2RX6 antibody PA2128 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated goat samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in goat brain in WB, you can get your next antibody for free.
Boster Scientific Support
Answered: 2019-10-02
Question
We are currently using anti-P2X6/P2RX6 antibody PA2128 for human tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on canine tissues as well?
Verified Customer
Verified customer
Asked: 2019-06-25
Answer
The anti-P2X6/P2RX6 antibody (PA2128) has not been tested for cross reactivity specifically with canine tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in canine you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2019-06-25
Question
Thank you for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for muscle of leg using anti-P2X6/P2RX6 antibody PA2128. Let me know if you need anything else.
Verified Customer
Verified customer
Asked: 2019-05-23
Answer
Thank you for the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2019-05-23