Anti-NHE-8 SLC9A8 Antibody

Product Name

Anti-NHE-8 SLC9A8 Antibody

View all NHE8 Antibodies

SKU/Catalog Number

A08467

Size

100μl

Form

Liquid

Description

Boster Bio Anti-NHE-8 SLC9A8 Antibody catalog # A08467. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NHE-8 SLC9A8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08467)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the C-terminal region of human NHE-8. at AA rangle: 420-500

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A08467 is reactive to SLC9A8 in Human, Mouse, Rat

Applications

A08467 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

65422 MW

Background of NHE8

This antibody is suitable for Cancer Research and drug resistance. It has been found that ABC transporters are involved in mulitdrug resistance through their ability to control the presence of drugs in cells. Multidrug resistance is currently being looked at in particular reference to cancer that is resistant to treatment. ABCB8 seems to have particularly high resistance rates in renal cancer and cancer of the central nervous system. Another significant aspect of ABCB8 is that it is a mitochondrial transporter. There are very few ABC transporters localized to the mitochondria which implies information about them could be extremely important. ABCB8 may also be localized to other parts of the cell which are yet to be determined. Anti-ABCB8 antibody is ideal for researchers interested in Cancer Research and drug resistance.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of Jurkat cells using NHE-8 Polyclonal antibody.

Gene/Protein Information For SLC9A8 (Source: Uniprot.org, NCBI)

Alternative Names

DKFZp686C03237; KIAA0939DKFZp686C03237; MGC138418; Na(+)/H(+) exchanger 8; NHE-8; NHE8FLJ42500; sodium/hydrogen exchanger 8; solute carrier family 9 (sodium/hydrogen exchanger); solute carrier family 9 (sodium/hydrogen exchanger), isoform 8; solute carrier family 9 (sodium/hydrogen exchanger), member 8; Solute carrier family 9 member 8 SLC9A8 NHE-8, NHE8 solute carrier family 9 member A8 sodium/hydrogen exchanger 8|Na(+)/H(+) exchanger 8|solute carrier family 9 (sodium/hydrogen exchanger), member 8|solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8

For more info on SLC9A8, check out the SLC9A8 Infographic

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In this infographic, you will see the following information for SLC9A8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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