Anti-Na+ CP type VIII Alpha SCN8A Antibody

Product Name

Anti-Na+ CP type VIII Alpha SCN8A Antibody

View all Nav1.6 Antibodies

SKU/Catalog Number

A02015

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Na+ CP type VIII Alpha SCN8A Antibody catalog # A02015. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Na+ CP type VIII Alpha SCN8A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02015)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human MEK-6 around the phosphorylation site of S207.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02015 is reactive to SCN8A in Human, Mouse, Rat

Applications

A02015 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

225280 MW

Background of Nav1.6

Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.

Chicheportiche Y., J. Biol. Chem. 272:32401-32410(1997).
Marsters S.A., Curr. Biol. 8:525-528(1998).
Clark H.F., Genome Res. 13:2265-2270(2003).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000

Validation Images & Assay Conditions

Click image to see more details

Western blot (WB) analysis of Na+ CP type VIIIα polyclonal antibody at 1:500 dilution
Lane1:MCF-7 cell lysate
Lane2:Raw264.7 cell lysate
Lane3:H9C2 cell lysate

Gene/Protein Information For SCN8A (Source: Uniprot.org, NCBI)

Alternative Names

CerIII; hNa6/Scn8a voltage-gated sodium channel; MED; NaCh6; Nav1.6; PN4; sodium channel protein type 8 subunit alpha; Sodium channel protein type VIII subunit alpha; sodium channel, voltage gated, type VIII, alpha polypeptide; sodium channel, voltage gated, type VIII, alpha subunit; Voltage-gated sodium channel subunit alpha Nav1.6 SCN8A BFIS5, CERIII, CIAT, DEE13, EIEE13, MED, MYOCL2, NaCh6, Nav1.6, PN4 sodium voltage-gated channel alpha subunit 8 sodium channel protein type 8 subunit alpha|hNa6/Scn8a voltage-gated sodium channel|sodium channel, voltage gated, type VIII, alpha subunit|voltage-gated sodium channel subunit alpha Nav1.6|voltage-gated sodium channel type VIII alpha protein

For more info on SCN8A, check out the SCN8A Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SCN8A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Take me to the SCN8A Infographic

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis