Anti-KAPCB PRKACB Antibody

Product Name

Anti-KAPCB PRKACB Antibody

View all PKA C beta Antibodies

SKU/Catalog Number

A05366

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-KAPCB PRKACB Antibody (Catalog # A05366). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-KAPCB PRKACB Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05366)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human KAPCB.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05366 is reactive to PRKACB in Human, Mouse, Rat

Reconstitution

Observed Molecular Weight

111 kDa

Calculated molecular weight

40623 MW

Background of PKA C beta

Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

Beebe S.J., Mol. Endocrinol. 4:465-475(1990).
Gregory S.G., Nature 441:315-321(2006).
Wu K.-J., Oncogene 21:7872-7882(2002).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A05366 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

Gene/Protein Information For PRKACB (Source: Uniprot.org, NCBI)

Alternative Names

cAMP-dependent protein kinase catalytic subunit beta;PKA C-beta;2.7.11.11;PRKACB; PRKACB CAFD2, PKA C-beta, PKACB protein kinase cAMP-activated catalytic subunit beta cAMP-dependent protein kinase catalytic subunit beta|protein kinase A catalytic subunit beta|protein kinase, cAMP-dependent, beta catalytic subunit|protein kinase, cAMP-dependent, catalytic, beta

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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