Anti-IL12RB1 Antibody Picoband®

Product Name

Anti-IL12RB1 Antibody Picoband®

View all IL-12 R beta 1 Antibodies

SKU/Catalog Number

A03401-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-IL12RB1 Antibody Picoband® catalog # A03401-1. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-IL12RB1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03401-1)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human IL12RB1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A03401-1 is reactive to IL12RB1 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

70 kDa

Calculated molecular weight

73109 MW

Background of IL-12 R beta 1

IL12RB1, mapped to 19p13.11, is also known as CD212. The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. And this protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A03401-1 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: HEPG2 whole cell

Validation Images & Assay Conditions

Gene/Protein Information For IL12RB1 (Source: Uniprot.org, NCBI)

Alternative Names

Interleukin-12 receptor subunit beta-1;IL-12 receptor subunit beta-1;IL-12R subunit beta-1;IL-12R-beta-1;IL-12RB1;IL-12 receptor beta component;CD212;IL12RB1;IL12R, IL12RB; IL12RB1 CD212, IL-12R-BETA1, IL12RB, IMD30 interleukin 12 receptor subunit beta 1 interleukin-12 receptor subunit beta-1|IL-12 receptor beta component|IL-12 receptor subunit beta-1|IL-12R subunit beta-1|cluster of differentiation 212|interleukin 12 receptor, beta 1|interleukin-12 receptor beta-1 chain

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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