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Product Info Summary
| SKU: | A15959-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-GRTP1 Antibody
SKU/Catalog Number
A15959-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-GRTP1 Antibody (Catalog # A15959-1). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
GRTP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-GRTP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A15959-1)
Host
Rabbit
Contents
GRTP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
GRTP1 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human GRTP1. The immunogen is located within the first 50 amino acids of GRTP1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of HIG2 are known to exist; this antibody will detect both isoforms. HIG2 antibody is predicted to not cross-react with HIG1
Reactive Species
A15959-1 is reactive to Grtp1 in Human, Mouse, Rat
Applications
A15959-1 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
38554 MW
Background of Grtp1
Growth hormone regulated TBC protein 1 (GRTP1) was identified through microarray analysis as a gene whose expression is regulated by growth hormone (GH). It contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. GRTP1 mRNA is expressed at highest levels in testes, and is also present in kidney, lung, liver, and intestine. Administration of GH to mice resulted in an increase in GRTP1 mRNA in testes, but a decrease of GRTP1 mRNA in kidney and liver. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment. At least three isoforms of GRTP1 are known to exist; this antibody should recognize all isoforms.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
GRTP1 antibody can be used for detection of GRTP1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of GRTP1 in K562 cell lysate with GRTP1 antibody at (A) 1 and (B) 2 μg/mL.
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Immunocytochemistry of GRTP1 in K562 cells with GRTP1 antibody at 2.5 μg/mL.
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Immunofluorescence of GRTP1 in K562 cells with GRTP1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For Grtp1 (Source: Uniprot.org, NCBI)
Gene Name
Grtp1
Full Name
Growth hormone-regulated TBC protein 1
Weight
38554 MW
Alternative Names
FLJ22474; growth hormone regulated TBC protein 1; growth hormone-regulated TBC protein 1; MGC138328; TBC1 domain family member 6; TBC1 domain family, member 6; TBC1D6MGC138330
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Grtp1, check out the Grtp1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Grtp1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GRTP1 Antibody (A15959-1)
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