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Product Info Summary
| SKU: | PA2249 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Glutamate receptor 3/GRIA3 Antibody Picoband®
View all Glutamate Receptor 3 Antibodies
SKU/Catalog Number
PA2249
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Glutamate receptor 3/GRIA3 Antibody catalog # PA2249. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Glutamate receptor 3/GRIA3 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2249)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human GRIA3, identical to the related mouse and rat sequences.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA2249 is reactive to GRIA3 in Human, Mouse, Rat
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
101 kDa
Calculated molecular weight
101157 MW
Background of Glutamate Receptor 3
Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. It is mapped to Xq25. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. In addition to that, GRIA3 has been shown to interact with GRIP1 and PICK1.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PA2249 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Mouse, Rat, Human
Positive Control
WB: Rat Brain Tissue, Mouse Brain Tissue
Validation Images & Assay Conditions
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Anti-GRIA3 antibody, PA2249, All Western blotting
All lanes: Anti-GRIA3 (PA2249) at 0.5ug/ml
Lane 1: Rat Brain Tissue Lysate at 40ug
Lane 2: Mouse Brain Tissue Lysate at 40ug
Predicted bind size: 101KD
Observed bind size: 101KD
Protein Target Info & Infographic
Gene/Protein Information For GRIA3 (Source: Uniprot.org, NCBI)
Gene Name
GRIA3
Full Name
Glutamate receptor 3
Weight
101157 MW
Superfamily
glutamate-gated ion channel (TC 1.A.10.1) family
Alternative Names
Glutamate receptor 3;GluR-3;AMPA-selective glutamate receptor 3;GluR-C;GluR-K3;Glutamate receptor ionotropic, AMPA 3;GluA3;GRIA3;GLUR3, GLURC; GRIA3 GLUR-C, GLUR-K3, GLUR3, GLURC, GluA3, MRX94, MRXSW glutamate ionotropic receptor AMPA type subunit 3 glutamate receptor 3|AMPA-selective glutamate receptor 3|dJ1171F9.1|gluR-3|glutamate receptor C|glutamate receptor subunit 3|glutamate receptor, ionotrophic, AMPA 3|glutamate receptor, ionotropic, AMPA 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GRIA3, check out the GRIA3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GRIA3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Glutamate receptor 3/GRIA3 Antibody Picoband® (PA2249)
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