Anti-GATA-6 monoclonal Antibody

Product Name

Anti-GATA-6 monoclonal Antibody

View all GATA-6 Antibodies

SKU/Catalog Number

M00778

Size

100ul

Form

Liquid

Description

Boster Bio Anti-GATA-6 monoclonal Antibody catalog # M00778. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-GATA-6 monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00778)

Host

Mouse

Contents

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Monoclonal

Clone Number

4E11C9

Isotype

IgG

Immunogen

Purified recombinant fragment of PBEF expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M00778 is reactive to GATA6 in Human

Applications

M00778 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

60033 MW

Background of GATA-6

TRPC6, also known as TRP6, short transient receptor potential channel 6 and transient receptor potential cation channel subfamily C member 6, is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC6 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C and may not to be activated by intracellular calcium store depletion. Defects in this gene are a cause of focal segmental glomerulosclerosis (FSGS). Expression of this protein has been reported in tissues such as placenta, lung, spleen, ovary, small intestine, and renal podocytes. Immunohistochemistry studies using polyclonal antibodies to this target have shown moderate to strong staining in cell types such as neurons, breast, respiratory, squamous and prostate epithelium, epidermis, placental trophoblasts, dendritic cells, and subsets of immune cells, and faint to moderate staining of adrenal, colon, ganglion cells, hepatocytes, heart, and testis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:200-1000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For GATA6 (Source: Uniprot.org, NCBI)

Alternative Names

GATA binding protein 6; GATA6; GATA-6; GATA-binding factor 6; GATA-binding protein 6; transcription factor GATA-6 GATA6 GATA binding protein 6 transcription factor GATA-6|GATA-binding factor 6

For more info on GATA6, check out the GATA6 Infographic

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In this infographic, you will see the following information for GATA6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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