Anti-Fos B/FOSB Antibody Picoband®

Product Name

Anti-Fos B/FOSB Antibody Picoband®

View all FosB/G0S3 Antibodies

SKU/Catalog Number

PA1478

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Fos B/FOSB Antibody catalog # PA1478. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Fos B/FOSB Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1478)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Fos B, identical to the related mouse and rat sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1478 is reactive to FOSB in Human, Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

24 kDa

Calculated molecular weight

35928 MW

Background of FosB/G0S3

FOSB, FBJ murine osteosarcoma viral oncogene homolog B, is a protein that, in humans, is encoded by the FOSB gene. FOSB is a member of Fos gene family which consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. The FOSB gene is mapped to 19q13.32. Delta FOSB is a truncated splice variant of FOSB. Delta FosB has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. Delta FosB also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA1478 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Positive Control

WB: HT1080 Cell, SW620 Cell, HELA Cell, SMMC Cell, MM453 Cell,

Validation Images & Assay Conditions

Gene/Protein Information For FOSB (Source: Uniprot.org, NCBI)

Alternative Names

Protein fosB;G0/G1 switch regulatory protein 3;FOSB;G0S3; FOSB AP-1, G0S3, GOS3, GOSB FosB proto-oncogene, AP-1 transcription factor subunit protein fosB|FBJ murine osteosarcoma viral oncogene homolog B|FosB proto-oncogene, AP-1 trancription factor subunit|G0/G1 switch regulatory protein 3|activator protein 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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