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Product Info Summary
| SKU: | A04566 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-COH1 VPS13B Antibody
SKU/Catalog Number
A04566
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-COH1 VPS13B Antibody (Catalog # A04566). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
COH1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-COH1 VPS13B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04566)
Host
Rabbit
Contents
COH1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
COH1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human COH1. The immunogen is located within amino acids 90 - 140 of COH1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least five alternatively spliced transcript variants have been observed. COH1 detects two isoforms.
Reactive Species
A04566 is reactive to VPS13B in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
448664 MW
Background of VPS13B
COH1 (Cohen syndrome protein 1), also known as VPS13B (vacuolar protein sorting-associated protein 13B) or CHS1, belongs to the VPS13 family and may function in vesicle-mediated transport and sorting of proteins within the cell. COH1 is widely expressed and multiple alternatively spliced transcript variants have been observed. Mutations in this gene have been associated with Cohen syndrome. COH1 is a Golgi-localized peripheral membrane protein and plays a critical role in Golgi (re)assembly.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04566 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
COH1 antibody can be used for detection of COH1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of COH1 in SK-N-SH cell lysate with COH1 antibody at (A) 1 and (B) 2 μg/mL.
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Immunofluorescence of COH1 in human brain tissue with COH1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For VPS13B (Source: Uniprot.org, NCBI)
Gene Name
VPS13B
Full Name
Vacuolar protein sorting-associated protein 13B
Weight
448664 MW
Superfamily
VPS13 family
Alternative Names
CHS1, COH1, CHS1, KIAA0532, Vacuolar protein sorting-associated protein 13B, Cohen syndrome protein 1 VPS13B CHS1, COH1 vacuolar protein sorting 13 homolog B vacuolar protein sorting-associated protein 13B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on VPS13B, check out the VPS13B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for VPS13B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-COH1 VPS13B Antibody (A04566)
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