Product Info Summary
SKU: | A02564 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-CNGA3 Antibody
SKU/Catalog Number
A02564
Size
100ul
Form
Liquid
Description
Boster Bio Anti-CNGA3 Antibody catalog # A02564. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CNGA3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02564)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human BAF250b
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02564 is reactive to CNGA3 in Human, Mouse, Rat
Applications
A02564 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
78838 MW
Background of CNGA3
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth By similarity. Binds DNA non-specifically.
Mungall A.J., Nature 425:805-811(2003).
Mangel L., J. Biol. Chem. 273:30466-30471(1998).
Imbert G., Nat. Genet. 14:285-291(1996).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
![a02564 anti cnga3 antibody wb testing 1 a02564 anti cnga3 antibody wb testing 1](https://www.bosterbio.com/media/catalog/product/a/0/a02564-anti-cnga3-antibody-wb-testing-1.jpg)
Click image to see more details
Figure 1. Western blotting validation for Anti-CNGA3 Antibody A02564
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For CNGA3 (Source: Uniprot.org, NCBI)
Gene Name
CNGA3
Full Name
Cyclic nucleotide-gated cation channel alpha-3
Weight
78838 MW
Superfamily
cyclic nucleotide-gated cation channel (TC 1.A.1.5) family
Alternative Names
CCNC1; CCNCa; CCNCalpha; CNCG3; CNG channel alpha-3; CNG-3; CNG3ACHM2; cone photoreceptor cGMP-gated channel alpha subunit; Cone photoreceptor cGMP-gated channel subunit alpha; cyclic nucleotide gated channel alpha 3; cyclic nucleotide-gated cation channel alpha-3; Cyclic nucleotide-gated channel alpha-3 CNGA3 ACHM2, CCNC1, CCNCa, CCNCalpha, CNCG3, CNG3 cyclic nucleotide gated channel subunit alpha 3 cyclic nucleotide-gated cation channel alpha-3|CNG channel alpha-3|CNG-3|cone photoreceptor cGMP-gated channel alpha subunit|cone photoreceptor cGMP-gated channel subunit alpha|cyclic nucleotide gated channel alpha 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CNGA3, check out the CNGA3 Infographic
![CNGA3 infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CNGA3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CNGA3 Antibody (A02564)
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