ABCB6 Antibodies

AND ABCB6 ELISA kits, ABCB6 Proteins

Many biological assays use antibodies to detect ABCB6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABCB6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABCB6 antibodies...

We validate the specificity of these antibodies to ABCB6 by testing them on tissues known to express ABCB6 positively and negatively. Browse below to find the ABCB6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ABCB6 Infographic by Boster Bio

All ABCB6 Products

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Product

Figures

Specificity

Applications

Price

Anti-ABCB6 Antibody Picoband®

1 Citations 7 Q&As

Human

IHC, ICC, WB

$370
Cat # PA1723
100 μg/vial

ABCB6 (NM_005689) Human Over-expression Lysate

Human

$628
Cat # LS010058
100 µg

ABCB6 Overview

Facts about ATP-binding cassette sub-family B member 6, mitochondrial.

ABCB6 3D structure. Source: alphafold

ATP-binding cassette sub-family B member 6, mitochondrial (ABCB6)

Binds heme and porphyrins and functions within their ATP- dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.

Gene Information

Human
Gene Name:	ABCB6
Uniprot:	Q9NP58
Entrez:	10058

Family

Belongs to:

ABC transporter superfamily

Alternative Names

ABC; ABC14; ABCB6; ATP-binding cassette, sub-family B (MDR/TAP), member 6; EC 3.6.3; EST45597; FLJ22414; LAN; MCOPCB7; Mitochondrial ABC transporter 3; mitochondrial; MTABC3; MTABC3ABC14; P-glycoprotein-related protein; PRP; Umat

Molecular Weight

Mass (kDA):
93.886 kDA

Genomic Context


Human

Location:	2q35
Sequence:	2; NC_000002.12 (219209772..219218958, complement)

Tissue Specificity

Widely expressed. High expression is detected in the retinal epithelium.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. localized to the endosome-like compartment and dendrite tips.

Diseases

Malignant Neoplasms
Neoplasms
Liver Carcinoma
Carcinoma
Prion Diseases
Malignant Neoplasm Of Breast
Anemia
Liver Neoplasms
Neoplasm Metastasis
Mammary Neoplasms
Malignant Neoplasm Of Liver
Acute Erythroblastic Leukemia
Leukemia

Hyperplasia
Microphthalmos
Non-neoplastic Disorder
Melanoma
Ataxia
Hypoxia
Sideroblastic Anemia

Pathways

Transport
Drug Resistance
Localization
Glycosylation
Cell Cycle
Cell Growth
Gene Silencing
Induction Of Apoptosis
Electron Transport
Electron Transport Chain
Dna Repair
Oxidative Phosphorylation
Response To Oxidative Stress

Methylation
Mitochondrial Translocation
Mitochondrial Transport
Posttranscriptional Gene Silencing
Oxygen Transport
Pathogenesis
Pachytene

PTMs

Glycosylation

Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABCB6

References

PMID: 10837493 by Mitsuhashi N., et al. MTABC3, a novel mitochondrial ATP-binding cassette protein involved in iron homeostasis.

PMID: 11955620 by Emadi-Konjin H.-P., et al. Isolation of a genomic clone containing the promoter region of the human ATP binding cassette (ABC) transporter, ABCB6.

1 Publications of Boster ABCB6 Antibodies & ELISA Kits

PubMed ID: 10.3390/cells10102549, New Insights into the Pivotal Role of Iron/Heme Metabolism in TLR4/NF-κB Signal...

*More publications can be found for each product on its corresponding product page