Human recombinant Galectin-16 protein, AF

LGALS16 protein, Human

Galectin-16 (Gal-16) is a lectin family member and is one of the prototype galectins, but it exists as a monomer, and it is remarkably different from other prototype galectins in β-galactoside binding. Like galectin-13 and galectin-14, Galectin-16 is expressed in the placenta, contributing to T cell apoptosis, immune regulation, and immune tolerance, which is indispensable for fetal development. The molecular mechanism has been demonstrated that galectin-16 forms complex with c-Rel, suggesting galectin-16-activated signal transduction pathways via the c-Rel hub in B or T cells at the maternal-fetal interface.

Product Info Summary

SKU: PROTA8MUM7-1
Size: 5ug,20ug,100ug
Origin Species: Human
Source: Escherichia coli
Application: Cell Culture

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Product Name

Human recombinant Galectin-16 protein, AF

View all LGALS16 recombinant proteins

SKU/Catalog Number

PROTA8MUM7-1

Size

5ug,20ug,100ug

Tag

His Tag (N-term)

Description

Galectin-16 (Gal-16) is a lectin family member and is one of the prototype galectins, but it exists as a monomer, and it is remarkably different from other prototype galectins in β-galactoside binding. Like galectin-13 and galectin-14, Galectin-16 is expressed in the placenta, contributing to T cell apoptosis, immune regulation, and immune tolerance, which is indispensable for fetal development. The molecular mechanism has been demonstrated that galectin-16 forms complex with c-Rel, suggesting galectin-16-activated signal transduction pathways via the c-Rel hub in B or T cells at the maternal-fetal interface.

Storage & Handling

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months. Avoid repeated freeze/thaw cycles.

Cite This Product

Human recombinant Galectin-16 protein, AF (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTA8MUM7-1)

Form

Lyophilized

Formulation

The protein was lyophilized from a 0.2 μm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.

Purity

>98% as determined by SDS-PAGE.

Predicted MW

16.576kDa

Molecular weight

The protein has a calculated MW of 17.4 kDa. The protein migrates as 18 kDa under reducing condition (SDS-PAGE analysis).

Activity

Testing in process

Endotoxin

<0.1 EU per 1 μg of the protein by the LAL method.

Amino Acid Sequence

SFLTVPYKLPVSLSVGSCVIIKGTLIDSSINEPQLQVDFYTEMNEDSEIAFHLRVHLGRRVVMNSREFGIWMLEENLHYVPFEDGKPFDLRIYVCLNEYEVKVNGEYIYAFVHRIPPSYVKMIQVWRDVSLDSVLVNNGRR with polyhistidine tag at the N-terminus.

Reconstitution

Centrifuge at 3000 rpm for 5 mins before opening. It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 100 μg/mL and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

Validation Images & Assay Conditions

Gene/Protein Information For LGALS16 (Source: Uniprot.org, NCBI)

Gene Name

LGALS16

Full Name

Galectin-16

Weight

16.576kDa

Alternative Names

LGALS16 LGALS16 galectin 16 galectin-16|beta-galactoside-binding lectin|lectin, galactoside-binding, soluble, 16

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

For more info on LGALS16, check out the LGALS16 Infographic

LGALS16 infographic

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In this infographic, you will see the following information for LGALS16: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].

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Size

Total: $77

SKU:PROTA8MUM7-1

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