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- Table of Contents
Facts about Protein Wnt-16.
Might be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).
Human | |
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Gene Name: | WNT16 |
Uniprot: | Q9UBV4 |
Entrez: | 51384 |
Belongs to: |
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Wnt family |
protein Wnt-16; wingless-type MMTV integration site family, member 16
Mass (kDA):
40.69 kDA
Human | |
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Location: | 7q31.31 |
Sequence: | 7; NC_000007.14 (121325367..121341104) |
Isoform Wnt-16b is expressed in peripheral lymphoid organs such as spleen, appendix, and lymph nodes, in kidney but not in bone marrow. Isoform Wnt-16a is expressed at significant levels only in the pancreas.
Secreted, extracellular space, extracellular matrix.
PMID: 10500199 by McWhirter J.R., et al. Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia.
PMID: 11095990 by Fear M.W., et al. Wnt-16a, a novel Wnt-16 isoform, which shows differential expression in adult human tissues.