WAPL Antibodies

AND WAPL ELISA kits, WAPL Proteins

Many biological assays use antibodies to detect WAPL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WAPL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WAPL antibodies...

We validate the specificity of these antibodies to WAPL by testing them on tissues known to express WAPL positively and negatively. Browse below to find the WAPL antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WAPL Infographic by Boster Bio

All WAPL Products

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Product

Figures

Specificity

Applications

Price

Anti-WAPL Rabbit Monoclonal Antibody

Human

IP, IF, ICC, WB

$370
Cat # M03684
100 μl/vial

Anti-WAPL/FOE Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03684-2
100 μg/vial

WAPL Overview

Facts about Wings apart-like protein homolog.

WAPL 3D structure. Source: alphafold

Wings apart-like protein homolog (WAPL)

Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister- chromatid resolution during early stages of mitosis.

Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.

Gene Information

Human
Gene Name:	WAPL
Uniprot:	Q7Z5K2
Entrez:	23063

Family

Belongs to:

WAPL family

Alternative Names

Wings apart-like protein homolog

Molecular Weight

Mass (kDA):
132.946 kDA

Genomic Context


Human

Location:	10q23.2
Sequence:	10; NC_000010.11 (86435256..86521816, complement)

Tissue Specificity

Isoform 1 is highly expressed in uterine cervix tumor. Isoform 2 is widely expressed with a high level in skeletal muscle and heart.

Subcellular Localizations

[Isoform 2]: Nucleus.; Nucleus. Chromosome. Cytoplasm. Associates with chromatin through the cohesin complex during interphase. Released in the cytoplasm from nuclear envelope breakdown until anaphase, it reaccumulates in nucleus at telophase.

Interacting Proteins

PDS5B
RAD21
STAG2

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WAPL

References

PMID: 15150110 by Oikawa K., et al. Expression of a novel human gene, human wings apart-like (hWAPL), is associated with cervical carcinogenesis and tumor progression.

PMID: 15383329 by Kwiatkowski B.A., et al. Identification and cloning of a novel chromatin-associated protein partner of Epstein-Barr nuclear protein 2.