Protein virilizer homolog Antibodies

AND VIRMA ELISA kits, Protein virilizer homolog Proteins

Many biological assays use antibodies to detect Protein virilizer homolog, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein virilizer homolog in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein virilizer homolog antibodies...

We validate the specificity of these antibodies to Protein virilizer homolog by testing them on tissues known to express VIRMA positively and negatively. Browse below to find the VIRMA antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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VIRMA Infographic by Boster Bio

All VIRMA Products

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Price

Anti-KIAA1429/VIRMA Antibody Picoband®

Human

ELISA, IF, IHC, ICC, WB

$370
Cat # A32283-1
100 μg/vial

VIRMA (NM_183009) Human Over-expression Lysate

Human

$960
Cat # LS025962
100 µg

VIRMA Overview

Facts about Protein virilizer homolog.

VIRMA 3D structure. Source: alphafold

Protein virilizer homolog (VIRMA)

Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification which plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:24981863, PubMed:29507755). Acts as a key regulator of m6A methylation by encouraging m6A methylation of mRNAs in the 3'-UTR close to the stop codon: recruits the catalytic core elements METTL3 and METTL14, thereby directing m6A methylation at specific sites (PubMed:29507755).

Required for mRNA polyadenylation through its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR close to the stop codon correlating with other polyadenylation (APA) (PubMed:29507755). .

Gene Information

Human
Gene Name:	VIRMA
Uniprot:	Q69YN4
Entrez:	25962

Family

Belongs to:

vir family

Alternative Names

Protein virilizer homolog

Molecular Weight

Mass (kDA):
202.025 kDA

Genomic Context


Human

Location:	8q22.1
Sequence:	8; NC_000008.11 (94487689..94553518, complement)

Subcellular Localizations

Nucleus speckle. Nucleus, nucleoplasm. Cytoplasm. Mainly nuclear with some fraction located in the cytoplasm. ZC3H13 is required to anchor component of the MACOM subcomplex, such as VIRMA, in the nucleus.

PTMs

Acetylation

Methylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VIRMA

References

PMID: 11156988 by Niessen M., et al. Molecular identification of virilizer, a gene required for the expression of the sex-determining gene Sex-lethal in Drosophila melanogaster.

PMID: 24100041 by Horiuchi K., et al. Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle.