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- Table of Contents
Facts about UDP-glucose:glycoprotein glucosyltransferase 1.
Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation. .
Human | |
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Gene Name: | UGGT1 |
Uniprot: | Q9NYU2 |
Entrez: | 56886 |
Belongs to: |
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glycosyltransferase 8 family |
FLJ21763; GT; HUGT1; UDP--Glc:glycoprotein glucosyltransferase; UDP-glucose ceramide glucosyltransferase-like 1; UDP-glucose glycoprotein glucosyltransferase 1; UGCGL1; UGGT; UGT1; UGTR
Mass (kDA):
177.19 kDA
Human | |
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Location: | 2q14.3 |
Sequence: | 2; NC_000002.12 (128091184..128195677) |
Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.
Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.
PMID: 10694380 by Arnold S.M., et al. Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity.
PMID: 23349634 by Cloutier P., et al. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.