UAP1 Antibodies

AND UAP1 ELISA kits, UAP1 Proteins

Many biological assays use antibodies to detect UAP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UAP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UAP1 antibodies...

We validate the specificity of these antibodies to UAP1 by testing them on tissues known to express UAP1 positively and negatively. Browse below to find the UAP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: SPAG4

UAP1 Infographic by Boster Bio

All UAP1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-UAP1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M09450-1
100 μl/vial

UAP1 (NM_003115) Human Over-expression Lysate

Human

$628
Cat # LS006675
100 µg

UAP1 Overview

Facts about UDP-N-acetylhexosamine pyrophosphorylase.

UAP1 3D structure. Source: alphafold

UDP-N-acetylhexosamine pyrophosphorylase (UAP1)

Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc.
Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more action towards GlcNAc-1-P.

Gene Information

Human
Gene Name:	UAP1
Uniprot:	Q16222
Entrez:	6675

Family

Belongs to:

UDPGP type 1 family

Alternative Names

AGX; AGX1; AGX2; Antigen X; EC 2.7.7; EC 2.7.7.23; EC 2.7.7.27; SPAG2; sperm associated antigen 2; Sperm-associated antigen 2; UDP-N-acetylhexosamine pyrophosphorylase; UDP-N-acteylglucosamine pyrophosphorylase 1

Molecular Weight

Mass (kDA):
58.769 kDA

Genomic Context


Human

Location:	1q23.3
Sequence:	1; NC_000001.11 (162561440..162599843)

Tissue Specificity

Widely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.

Subcellular Localizations

Cytoplasm. In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UAP1

References

PMID: 8025165 by Diekman A.B., et al. Characterization of a human antigen with sera from infertile patients.

PMID: 9603950 by Mio T., et al. The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases: gene cloning, protein expression, and catalytic mechanism.