TMC2 Antibodies

AND TMC2 ELISA kits, TMC2 Proteins

Many biological assays use antibodies to detect TMC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TMC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TMC2 antibodies...

We validate the specificity of these antibodies to TMC2 by testing them on tissues known to express TMC2 positively and negatively. Browse below to find the TMC2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TMC2 Infographic by Boster Bio

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TMC2 (NM_080751) Human Over-expression Lysate

Human

$960
Cat # LS117532
100 µg

TMC2 Overview

Facts about Transmembrane channel-like protein 2.

TMC2 3D structure. Source: alphafold

Transmembrane channel-like protein 2 (TMC2)

Probable ion channel required for the normal function of cochlear hair cells (PubMed:11850618). Component of the hair cell's mechanotransduction (MET) machinery.

Involved in mechanosensitive responses of the hair cells (By similarity). .

Gene Information

Human
Gene Name:	TMC2
Uniprot:	Q8TDI7
Entrez:	117532

Family

Belongs to:

TMC family

Alternative Names

Transmembrane channel-like protein 2

Molecular Weight

Mass (kDA):
102.61 kDA

Genomic Context


Human

Location:	20p13
Sequence:	20; NC_000020.11 (2536607..2641784)

Tissue Specificity

Detected in fetal cochlea.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Localized to the stereocilia of the cochlear hair cells.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TMC2

References

PMID: 11850618 by Kurima K., et al. Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function.