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, No Gclids
SCYL1 Antibodies
AND SCYL1 ELISA kits, SCYL1 Proteins
Many biological assays use antibodies to detect SCYL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SCYL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SCYL1 antibodies...
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SCYL1 Infographic by Boster Bio
All SCYL1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, WB
$405
Cat # A04750
100ul
Cat # A04750
100ul
SCYL1 Overview
Facts about N-terminal kinase-like protein.
N-terminal kinase-like protein (SCYL1)
Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum (PubMed:18556652). Involved in the maintenance of the Golgi apparatus morphology (PubMed:26581903).
Has no detectable kinase activity in vitro (PubMed:18556652). .
Gene Information
| Human | |
|---|---|
| Gene Name: | SCYL1 |
| Uniprot: | Q96KG9 |
| Entrez: | 57410 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
Coated vesicle-associated kinase of 90 kDa; CVAK90; GKLPTelomerase transcriptional element-interacting factor; likely ortholog of mouse N-terminal kinase-like protein; MGC78454; NKTL; N-terminal kinase-like protein; NTKLN-terminal kinase-like; P105; SCY1-like 1 (S. cerevisiae); TAPKTeratoma-associated tyrosine kinase; TEIFSCY1-like protein 1; Telomerase regulation-associated protein; telomerase transcriptional elements-interacting factor; TRAPHT019
Molecular Weight
Mass (kDA):
89.631 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q13.1 |
| Sequence: | 11; NC_000011.10 (65525081..65538710) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus, cis-Golgi network. Localized to the Endoplasmic reticulum-Golgi intermediate and cis-Golgi in an ARF1-independent manner.; [Isoform 1]: Cytoplasm. Cytoplasmic throughout the cell cycle.; [Isoform 2]: Cytoplasm. Cytoplasmic throughout the cell cycle.; [Isoform 3]: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic during interphase and centrosomal during mitosis, it localizes to the centrosomes in a microtubule-indepen
Diseases
- Carcinoma
- Neoplasms
- Malignant Neoplasms
- Atrophy
- Nerve Degeneration
- Malignant Paraganglionic Neoplasm
- Neurodegenerative Disorders
- Glaucoma, Open-angle
- Sarcoma
- Glaucoma
- Nervousness
- Cell Transformation, Neoplastic
Interacting Proteins
- AXIN1
Pathways
- Localization
- Transport
- Mitosis
- Cell Cycle
- Regulation Of Macroautophagy
- Cell Proliferation
- Golgi Localization
- Cellular Homeostasis
- Immune Response
- Mesoderm Formation
- Membrane Budding
- Nuclear Export
- Cardiac Cell Differentiation
PTMs
Research Areas
- Protein Kinase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SCYL1
bosterbio.com/bosterbio-gene-info-cards/SCYL1
References
PMID: 12036289 by Kato M., et al. Identification and characterization of the human protein kinase-like gene NTKL: mitosis-specific centrosomal localization of an alternatively spliced isoform.
PMID: 15504359 by Tang Z., et al. Molecular cloning and characterization of a human gene involved in transcriptional regulation of hTERT.