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- Table of Contents
1 Citations 1 Q&As
1 Citations 6 Q&As
Facts about Signal transducer and activator of transcription 5B.
Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation.
Human | |
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Gene Name: | STAT5B |
Uniprot: | P51692 |
Entrez: | 6777 |
Belongs to: |
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transcription factor STAT family |
signal transducer and activator of transcription 5B; STAT5; STAT5b; transcription factor STAT5B
Mass (kDA):
89.866 kDA
Human | |
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Location: | 17q21.2 |
Sequence: | 17; NC_000017.11 (42199177..42288437, complement) |
Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
PMID: 8732682 by Silva C.M., et al. Characterization and cloning of STAT5 from IM-9 cells and its activation by growth hormone.
PMID: 8631883 by Lin J.-X., et al. Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.
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