This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Organic solute transporter subunit beta.
Modulates SLC51A glycosylation, membrane trafficking and stability actions. .
Human | |
---|---|
Gene Name: | SLC51B |
Uniprot: | Q86UW2 |
Entrez: | 123264 |
Belongs to: |
---|
OST-beta family |
Organic solute transporter subunit beta
Mass (kDA):
14.346 kDA
Human | |
---|---|
Location: | 15q22.31 |
Sequence: | 15; NC_000015.10 (65045387..65053397) |
Widely expressed with a high expression in ileum. Expressed in testis, colon, liver, small intestine, kidney, ovary and adrenal gland; and at low levels in heart, lung, brain, pituitary, thyroid gland, uterus, prostate, mammary gland and fat.
Cell membrane; Single-pass membrane protein. Mainly restricted to the lateral and basal membranes of ileal enterocytes.
PMID: 12719432 by Seward D.J., et al. Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta.
PMID: 16317684 by Ballatori N., et al. OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia.