SI Antibodies

AND SI ELISA kits, SI Proteins

Many biological assays use antibodies to detect SI, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SI in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SI antibodies...

We validate the specificity of these antibodies to SI by testing them on tissues known to express SI positively and negatively. Browse below to find the SI antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SI Infographic by Boster Bio

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Anti-SI Antibody Picoband®

13 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # A04542-1
100 μg/vial

SI Overview

Facts about Sucrase-isomaltase, intestinal.

SI 3D structure. Source: alphafold

Sucrase-isomaltase, intestinal (SI)

Plays an important role in the final stage of carbohydrate digestion. Isomaltase action is specific for both alpha-1,4- and alpha-1,6-oligosaccharides.

Gene Information

Human
Gene Name:	SI
Uniprot:	P14410
Entrez:	6476

Family

Belongs to:

glycosyl hydrolase 31 family

Alternative Names

EC 3.2.1.20; MGC131621; MGC131622; oligosaccharide alpha-1,6-glucosidase; sucrase-isomaltase (alpha-glucosidase); sucrase-isomaltase; sucrase-isomaltase, intestinal

Molecular Weight

Mass (kDA):
209.453 kDA

Genomic Context


Human

Location:	3q26.1
Sequence:	3; NC_000003.12 (164978898..165078496, complement)

Tissue Specificity

Expressed in the poorly differentiated crypt cells of the small intestine as well as in the mature villous cells. Expressed at very low levels in the colon.

Subcellular Localizations

Apical cell membrane; Single-pass type II membrane protein. Brush border.

Diseases

Neoplasms
Pain
Malignant Neoplasms
Insulin Sensitivity
Hiv Infections
Cerebrovascular Accident
Insulin Resistance
Diabetes Mellitus
Tissue Adhesions
Depressive Disorder
Hypertensive Disease
Carcinoma

Fracture
Immunologic Deficiency Syndromes
Cardiovascular Diseases
Inflammation
Diabetes Mellitus, Non-insulin-dependent
Obesity
Infarction

Pathways

Transport
Localization
Secretion
Pathogenesis
Immune Response
Cell Proliferation
Insulin Secretion
Excretion
Aging
Sensitization
Lymphocyte Proliferation
Tropism
Fertilization

Cell Death
Regeneration
Cell Adhesion
Pollination
Reflex
Cell Growth
Mating

PTMs

Oxidation
Cleavage
Phosphorylation
Nitration
Reduction
Glycosylation
Methylation
Biotinylation
Carboxylation
Hydroxylation

Acetylation
Bromination
Amidation
Amination
Demethylation
Ubiquitination
Deglycosylation
Sulphation
Citrullination
Sumoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SI

References

PMID: 1353958 by Chantret I., et al. Sequence of the complete cDNA and the 5' structure of the human sucrase-isomaltase gene. Possible homology with a yeast glucoamylase.

PMID: 2962903 by Green F., et al. Isolation of a cDNA probe for a human jejunal brush-border hydrolase, sucrase-isomaltase, and assignment of the gene locus to chromosome 3.