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- Table of Contents
Facts about Seizure protein 6.
Involved in the development of appropriate excitatory synaptic connectivity. .
Mouse | |
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Gene Name: | Sez6 |
Uniprot: | Q7TSK2 |
Entrez: | 20370 |
Belongs to: |
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SEZ6 family |
BSRPC; BSRP-C; hSEZ-6; seizure related 6 homolog (mouse); SEZ6
Mass (kDA):
107.433 kDA
Mouse | |
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Location: | 11 B5|11 46.74 cM |
Sequence: | 11; |
Brain-specific. Expressed in extrasynaptic and synaptic subcellular fractions (at protein level). Expression correlates with the most active periods of cortical neurogenesis and neuronal maturation. Expression is restricted to the gray matter with higher levels in the forebrain including the olfactory bulb, anterior olfactory nuclei, olfactory tubercle, striatum, hippocampal CA1 pyramidal cell layer and cerebral cortex. Expression is up-regulated with the convulsant drug, pentylenetetrazole.
PMID: 7488116 by Shimizu-Nishikawa K., et al. Cloning and characterization of seizure-related gene, SEZ-6.
PMID: 7723619 by Shimizu-Nishikawa K., et al. Cloning and expression of SEZ-6, a brain-specific and seizure-related cDNA.