SAMSN1 Antibodies

AND SAMSN1 ELISA kits, SAMSN1 Proteins

Many biological assays use antibodies to detect SAMSN1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SAMSN1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SAMSN1 antibodies...

We validate the specificity of these antibodies to SAMSN1 by testing them on tissues known to express SAMSN1 positively and negatively. Browse below to find the SAMSN1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SAMSN1 Infographic by Boster Bio

All SAMSN1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SAMSN SAMSN1 Antibody

Human

ELISA, IF, ICC, WB

$449
Cat # A08977
0.1 mg

Human SAMSN1 Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ9NSI8
Starting from 10ug

Anti-SAMSN1 Mouse Monoclonal Antibody [Clone ID: OTI7F5]

Human

IHC, WB

$523
Cat # M08977
100 µl

SAMSN1 (NM_022136) Human Over-expression Lysate

Human

$628
Cat # LS064092
100 µg

Anti-SAMSN1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A08977-2
100 μg/vial

SAMSN1 Overview

Facts about SAM domain-containing protein SAMSN-1.

SAMSN1 3D structure. Source: alphafold

SAM domain-containing protein SAMSN-1 (SAMSN1)

Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro).

Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization.

Gene Information

Human
Gene Name:	SAMSN1
Uniprot:	Q9NSI8
Entrez:	64092

Family

Belongs to:

No superfamily

Alternative Names

HACS1gene with homology to KIAA0790 protein10NASH1; Hematopoietic adaptor containing SH3 and SAM domains 1; SAM and SH3 domain containing 1; SAM and SH3 domain containing 2; SAM domain, SH3 domain and nuclear localisation signals, 1; SAM domain, SH3 domain and nuclear localization signals 1; SAM domain, SH3 domain and nuclear localization signals protein 1; SAM domain-containing protein SAMSN-1; SH3D6B; SH3-SAM adaptor protein

Molecular Weight

Mass (kDA):
41.708 kDA

Genomic Context


Human

Location:	21q11.2
Sequence:	21; NC_000021.9 (14485228..14583402, complement)

Tissue Specificity

Detected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood.

Subcellular Localizations

Nucleus. Cytoplasm. Cell projection, ruffle. Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles (By similarity).

Diseases

Malignant Neoplasms
Multiple Myeloma
Down Syndrome
Myeloid Leukemia
Leukemia
Hematopoietic Neoplasms
Malignant Neoplasm Of Lung
Carcinogenesis
Carcinoma
Ulcer
Leukemia, Myelocytic, Acute
Chronic Disease/disorder
Neoplasms

Chromosome Breakage
Lymphoma
Colorectal Cancer
Cytogenetic Abnormality
Colitis
Left-sided Displacement Of Abomasum
Neuroblastoma

Pathways

Localization
Cell Activation
B Cell Activation
Transport
Cell Proliferation
Cell Differentiation
Vesicle-mediated Transport
Rna Processing
B Cell Proliferation

B Cell Differentiation
Pathogenesis
Secretion

PTMs

Phosphorylation

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SAMSN1

References

PMID: 11536050 by Claudio J.O., et al. HACS1 encodes a novel SH3-SAM adaptor protein differentially expressed in normal and malignant hematopoietic cells.

PMID: 11594764 by Uchida T., et al. Identification of Nash1, a novel protein containing a nuclear localization signal, a sterile alpha motif, and an SH3 domain preferentially expressed in mast cells.